TRAF interacting protein

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TRAIP
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TRAIP, RNF206, TRIP, SCKL9, TRAF interacting protein
External IDs MGI: 1096377 HomoloGene: 31343 GeneCards: TRAIP
RNA expression pattern
PBB GE TRAIP 205598 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005879

NM_011634

RefSeq (protein)

NP_005870

NP_035764.2
NP_035764

Location (UCSC) Chr 3: 49.83 – 49.86 Mb Chr 9: 107.95 – 107.97 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

TRAF-interacting protein is a protein that in humans is encoded by the TRAIP gene.[3][4]

This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.[4]

Interactions[edit]

TRAF interacting protein has been shown to interact with FLII,[5] TRAF1[3] and TRAF2.[3]

References[edit]

Further reading[edit]

External links[edit]