TRNA (guanine6-N2)-methyltransferase
| TRNA (guanine6-N2)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.256 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
TRNA (guanine6-N2)-methyltransferase (EC 2.1.1.256, methyltransferase Trm14, m2G6 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine6-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine6 in tRNA S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA
The enzyme specifically methylates guanine6 at N2 in tRNA.
References
- ^ Menezes, S.; Gaston, K.W.; Krivos, K.L.; Apolinario, E.E.; Reich, N.O.; Sowers, K.R.; Limbach, P.A.; Perona, J.J. (2011). "Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14". Nucleic Acids Res. 39: 7641–7655. doi:10.1093/nar/gkr475. PMID 21693558.
External links
- TRNA+(guanine6-N2)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)