Talk:Advanced glycation end-product

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FAQ[edit]

I removed the following text from the article:

Are there medications that reduce circulating AGEs ? (For example, mimicking RAGE (AGE receptors) to competitively inhibit circulating AGE ?)

Answering this question might be nice for the article. linas 00:52, 12 June 2007 (UTC)

Opening paragraph[edit]

Somebody expressed confusion over the distinction between glycosylation and glycation. I don't know why that needs to be in the article, but it certainly doesn't deserve to be included in the opening paragraph. Unfree (talk) 16:29, 7 May 2008 (UTC)


Can the intro confirm that AGE are modified/damaged/glycated proteins ? Rod57 (talk) 11:54, 7 December 2010 (UTC)


Here is such info. But everywhere on the web there is stuff on glycated proteins after all.--Loki0115 (talk) 12:17, 7 December 2010 (UTC)

AGE formation in Other Diseases[edit]

I added new section about AGEs and other diseases with references. AGEs have been implicated in a number of pathological conditions which is not known to the general public. More important is that there are diet changes that can lower AGE production and hence risk. DanielGlazer (talk) 06:30, 7 June 2009 (UTC)

Primary sources[edit]

Although the research on AGEs is quite fascinating, let's remember that this is a general encyclopaedia. AGE disease implications, especially pronouncements about AGE-related "anti-aging" therapies, remain speculative at the moment. Research reported in only one or two primary sources is probably not of sufficient notability for Wikipedia. Let's try to avoid these problems by sourcing the article with good reviews. Keepcalmandcarryon (talk) 05:42, 22 June 2009 (UTC)

recent edits by User:GeorgeLouis[edit]

Over the past couple of days User:GeorgeLouis has made some pretty extensive changes as per this set of difs. Some of these are improvements but several rely on sources from Life extension advocates and a) fail WP:MEDRS and b) give too much WP:WEIGHT to those advocate's perspective. The page is still under construction as per the tag which requests others to hang back, so I am not intervening, except to add this note, a note on georgelewis' Talk page, and the medical citations needed tag that I added today to the article. Jytdog (talk) 12:20, 13 November 2013 (UTC)

I pored over the article and at the request of an editor and believe that all the information is cited to WP:Reliable sources (except where a tag specifically calls for a quality cite), and I don't even know what a "life extension" advocate is. Anybody can edit the result. Yours sincerely, GeorgeLouis (talk) 16:05, 13 November 2013 (UTC)
yep, if you just do a plain google search you get all the longevity nonsense; it is exactly because this sort of thing happens with alt med topics, that MEDRS exists, and is important. If you don't want to fix the changes you made, I will probably just revert the ones that made the article less reliable as per MEDRS.Jytdog (talk) 16:33, 13 November 2013 (UTC)
went through and fixed the damage. its ok now. as i said many of the changes were improvements.. just some bad sources.Jytdog (talk) 00:38, 14 November 2013 (UTC)
Thanks GeorgeLouis for your continuing edits, and Jytdog for your revisions. This article is looking 100% better from the impenetrable state it was written in previously! --LT910001 (talk) 02:24, 14 November 2013 (UTC)

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External links modified[edit]

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