Talk:Brain-derived neurotrophic factor

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Errors?[edit]

Hi User:Cbyrd2011. What is inaccurate about the current content at Brain-derived_neurotrophic_factor#Val66Met, in your view? Jytdog (talk) 00:49, 4 April 2017 (UTC)

Is there a reason you are seeking me out for an edit war? I deliberately left your unprofessional edit and asked for help in the matter because you are obviously not one to mess with. So the question really is: why did you delete all of my contribution, without following training guidelines? What was inaccurate about my content, in your view? By the way, "Horrible ref. names" and the mention of how val/ val and met/ met are obviously not the same are not efficient enough reasons to delete my whole post, I would argue many will agree with me if you had followed guidelines and mentioned what and why you were going to change things, as I did. Cbyrd2011 (talk) 00:57, 4 April 2017 (UTC)
I would really prefer you put back my content, and then we can discuss errors.
First of all, please read WP:BRD; what is happening is entirely normal. With regard to discussion here on the talk page, please read and follow WP:FOC.
Here is your edit; much of it is still there. I did remove the following:

In Val/Val homozygotes, the most abundant BDNF transcripts in hippocampal neurons (exons 1, 2, 4, & 6) can be found throughout the cell. For example, knockout studies have shown that exon 1 and 4 are essential for dendrites close to the soma while exons 2 and 6 shape distal dendrites. In Val/Met heterozygotes, however, all 4 transcripts can be found in the cell body, producing small, fat neurons with relatively no protrusions. This indicates that BDNF mRNA is not being transported to the dendrites for transcription, and is thus transcribed in the soma, producing an enlarged cell body with few protrusions. The few dendrites formed are drastically underdeveloped. As expected, Met/Met homozygotes are also affected with similar findings to heterozygotes.

As noted in my edit note, this is unsourced. I withdraw the objection that it doesn't make sense - it does. So - it is here on the talk page, per WP:PRESERVE. You can restore it but you need to provide a reliable source per WP:BURDEN.
Please identify any problems with the current content. You said here that there are errors in it. Jytdog (talk) 01:43, 4 April 2017 (UTC)
Ah, you got that from the Frontiers ref. Added back a shortened version of that here. I am really glad you introduced this subject matter -- it was needed! Jytdog (talk) 05:32, 4 April 2017 (UTC)

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