Talk:Desflurane

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Pharmacology

Articles indicate that desflurane undergoes negligible metabolism, which is perhaps more correct than stating that this drug is not metabolized. This is of particular importance when considering hepatotoxicity. Njoku D et.al. state that desflurane undergoes biotransformation when exposed to hepatic cytochrome P450, rendering metabolites that can trigger immunologic hepatitis in patients; such a case is described by Berghaus et.al. Baitisj (talk) 02:13, 23 August 2015 (UTC)[reply]

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