Talk:Hyperinsulinemia

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 3 September 2020 and 14 December 2020. Further details are available on the course page. Student editor(s): Bautis35.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 00:08, 17 January 2022 (UTC)

Untitled

As part of my ales204 class, I Dtostenson will be working on this stub to make it a full article :D I Added the introductory paragraphs and added a wonderful picture courtesy of the isulin page — Preceding unsigned comment added by DTostenson (talk • contribs) 05:08, 8 November 2011 (UTC)

Hope this is the place for this. I don't know the answer but it seems to me that hyperinsulinemia might also be caused by reduced ability to eliminate insulin. Some information on the possible metabolic fates of insulin would be usefull. Mattrix9999 (talk) 06:44, 16 July 2012 (UTC)

I think that there is a problem in the next sentence ("Treatment" chapter)

"Another method used to lower excessively high insulin levels is organic Cinnamon as was demonstrated when supplemented in clinical human trials.[10]"

The problem is that the sentence doesn't clearify that Organic (Chinese) cinnamon might be good only in cases where there is Insulin resistance, but might not be effective in Hyperinsulinemia that doesn't include IR. Ben-Natan (talk) 04:08, 19 February 2015 (UTC)

• The only thing I am qualified to comment on here is the grammar. The sentence should read, "Another method used to lower excessively high insulin levels is organic cinnamon, which fact was demonstrated by supplementation in clinical human trials."

I can also say that both myself and my father (as well as his mother and his brothers and many of their children) all developed type II diabetes, and that while I don't use it, my father swears by cinnamon. I'll ask for comment when next I see my primary care provider or endocrinologist. μηδείς (talk) 22:01, 19 February 2015 (UTC)

I can't really argue with the deletion. I didn't look at the fulltext of the paper, but it wasn't clear that they were measuring hyperinsulinemia directly, only insulin sensitivity. You can assume ... but in biology, you can't assume. Besides, the usual crowd would complain it's primary, not MEDRS, etc. Nonetheless I think it is probably true. Cinnamon and cassia (sold as 'cinnamon' in the U.S., maybe elsewhere) have a long history of use for diabetes in Chinese traditional medicine, which I believe has achieved a great deal of success through trial and error over the course of history. Apart from a range of powerful chemical compounds, note that dietary fiber is mentioned in the article now, and one teaspoon of cinnamon contains 10% of the recommended daily dose of fiber, according to our articles (2.5 grams, 20-35 grams) Wnt (talk) 02:23, 20 February 2015 (UTC)

The source states that cinnamon may have insulin-potentiating effects, then why does the quoted sentence state that it is used to lower insulin levels? It seems to be the other way. About the WP:MEDRS discussion, my feeling is that seven people is not a large enough population to take conclusions from. I think that the article here is giving undue WP:WEIGHT on this ("Another method used to lower excessively high insulin levels..." from a primary source wich is a very preliminar trial). I feel that this bit of text should be deleted or reworded heavily to reflect what the source actually states. --Tilifa Ocaufa (talk) 11:50, 21 February 2015 (UTC)

If C.Cassia works like weak insulin it might suit as treatment for Hyperinsulinemia as a Competitive antagonist. If, on the contrary, it works almost or exactly like Inslin - it's an Agonist, and could worsen cases of Hyperisnulinemia because it will raise the level of Inslin agency in the Bloodstram. A Biochemist\Endocrinologist\Nutritionist with knowledge of this pathology should give a strong word here... Ben-Natan (talk) 10:48, 22 February 2015 (UTC)

I should explain that the assumption is that the pancreas itself will not normally put a person into hypoglycemia. So making insulin more potent means that the levels of insulin in the blood will be decreased. Commonly, hyperinsulemia is simply a diagnostic test to show that someone is on the path to diabetes - it shows that the pancreas already needs to strain to get the message out to have sugar taken up. The elevated levels of C-peptide may even be beneficial. The exception is insulinoma (also Congenital hyperinsulinism) - but such people have hypoglycemia, not diabetes, and so would not be expected to benefit from cinnamon/cassia, I think. But all this is "OR" mixed with outright speculation; I'm not suggesting this is article content, just trying to clear up the apparent contradiction. Stick to the sources and exactly what they say! Wnt (talk) 18:14, 23 February 2015 (UTC)

Merge with Hyperinsulinism ?

Seems like the same. 176.12.137.189 (talk) 12:04, 22 February 2015 (UTC)

Yes, these should be merged. Wnt (talk) 18:16, 23 February 2015 (UTC)

I support the merge. In fact Hyperinsulinism should be merged into this article. Diptanshu^Talk 07:42, 24 February 2015 (UTC)

The choice of name is ... a really pedantic but not meaningless issue. "Hyperinsulinism" is, so far as I know, the overproduction of insulin as a trait, e.g. a genetic trait, and occurs in the cells of the pancreas. [1] Hyperinsulinemia is a higher level of insulin in the blood. So I suppose (this is a guess, do not use in the article without confirming!) that a person could have hyperinsulinism, but develop an anti-insulin neutralizing antibody somehow, and end up clearing enough insulin from the bloodstream to have a normal blood level, in which case he would have the ism but not the emia. However, if this distinction can be made, it won't take more than a few sentences, which leaves no big reason not to have one article... whatever you call it. Wnt (talk) 23:38, 24 February 2015 (UTC)

Misinformation driven by processed food industry and pharmaceuticals.

The production of insulin, with respect to dietary intake, is most markedly increased in response to carbohydrates. Low-carbohydrate-high-fat (LCHF) diets (such as the ketogenic diet) have been shown in multiple studies to successfully reverse many diseases directly caused by hyperinsulinemia as a result of insulin-resistance. This approach offers a non-pharmacological intervention that carries multiple health benefits, and by virtue of being a dietary intervention, does not require medication. It is for this reason, however, that LCHF/ketogenic diets have been, over the years, discouraged, because of the probable financial impact of this natural intervention on pharmaceutical companies and the processed food/cereal industry.

Suppression of the benefits of high fat, and animal-based diets, with concurrent promotion of unhealthy diets consisting primarily of grains, cereals and carbohydrates, have occurred since the time of John Harvey Kellogg in the early 20th century, driven by religious ideology and dogma, specifically the 7th Day Adventist denomination. The financial interests of many processed food companies and pharmaceutical companies have driven dietary guidelines for the past 100 years, and hence have led the Western World to the highest rates of type 2 diabetes, hypertension, cardiovascular disease, autoimmune disease and obesity in history.

Discuss. Dr.JT23 (talk) 14:20, 10 July 2022 (UTC)