Terri Attwood

From Wikipedia, the free encyclopedia

Terri Attwood
Teresa K. Attwood

(1959-11-20) 20 November 1959 (age 64)[4]
Alma materUniversity of Leeds
Known for
AwardsRoyal Society University Research Fellowship 1993–2002[1]
Scientific career
Protein fingerprinting
ThesisChromonic mesophases (1984)
Doctoral advisorJohn E. Lydon[2]
Doctoral students

Teresa K. Attwood is a professor of Bioinformatics in the Department of Computer Science and School of Biological Sciences at the University of Manchester and a visiting fellow at the European Bioinformatics Institute (EMBL-EBI).[5] She held a Royal Society University Research Fellowship at University College London (UCL) from 1993 to 1999 and at the University of Manchester from 1999 to 2002.[1]


Attwood gained her Bachelor of Science in Biophysics from the University of Leeds in 1982.[6] She was awarded a PhD, also in Biophysics, two years later, in 1984[2] under the supervision of John E. Lydon[7] studying chromonic mesophases.

Research and career[edit]

Attwood undertook postdoctoral research at Leeds until 1993, when she moved to University College London[8] for five years before moving to the University of Manchester in 1999. Her research[9][10] concerns protein sequence alignment and protein analysis.

Inspired by the creation of PROSITE, Attwood developed a method of protein fingerprinting and used this to establish the PRINTS[11][12][13] database. With Amos Bairoch she sought to unify work on protein family classification and annotation, eventually jointly securing a European Union grant with Rolf Apweiler to establish InterPro,[14][15] with Pfam, ProDom and Swiss-Prot/TrEMBL as consortium partners in 1997.[16]

Attwood has led major projects including the BioMinT FP5[17] text-mining consortium, the EMBER[18] bioinformatics education consortium (including EBI and Swiss Institute of Bioinformatics as partners), and the EPSRC PARADIGM Platform.[19] She is the Manchester principal investigator on projects SeqAhead (Next-generation sequencing data analysis network)[20] and AllBio (bioinformatics infrastructure for unicellular, animal and plant sciences),[21] and was also Manchester PI on EMBRACE[22] and EuroKUP (kidney and urine proteomics).[23] Attwood was a member of ELIXIR's Bioinformatics Training Strategy Committee (Work Package 11)[24] during ELIXIR's preparatory phase. She is currently Chair of the EMBnet Global Bioinformatics Network, she was a member of the Executive Committees of the International Society for Biocuration, and the Bioinformatics Training Network, and was recently elected to the Board of Directors of the International Society for Computational Biology. In 2012, she spearheaded the establishment of a GOBLET (Global Organisation for Bioinformatics Learning, Education and Training), with the major bioinformatics, computational biology and biocuration societies, networks and organisations as partners. As of 2016, Attwood is the Chair of the GOBLET Executive Board.[25][26]

As well as being a biocurator[16][27] she has co-developed tools to align and visualise protein sequences and structures, including Ambrosia and CINEMA.[28][29] The group are building re-usable software components to create useful bioinformatics applications through UTOPIA (Bioinformatics tools),[30][31] and are developing new approaches for automatic annotation and text mining, like PRECIS,[32] METIS,[33] BioIE,[34] and semantic approaches to data integration,[35] such as the Semantic Biochemical Journal[36] published by Portland Press. The UTOPIA tools underpin both the Semantic Biochemical Journal and a collaborative project with Pfizer and AstraZeneca to develop a 21st-century interface to biomedical literature and data management.

Attwood's research has received funding from the Engineering and Physical Sciences Research Council,[37] the Biotechnology and Biological Sciences Research Council, the Wellcome Trust, the Royal Society, the European Union and industry.[6]


Attwood teaches on undergraduate and postgraduate courses and has been doctoral advisor or co-supervisor to several PhD students (e.g., Manuel Corpas). Attwood has co-authored several book chapters and three popular bioinformatics textbooks: Introduction to Bioinformatics[38] and Bioinformatics and Molecular Evolution.[39] Attwood is a co-author of the bioinformatics textbook Bioinformatics Challenges at the Interface of Biology and Computer Science: Mind the Gap[40] with Steve Pettifer and Dave Thorne.

Academic service[edit]

Attwood serves on the editorial board of the Biochemical Journal,[41] Database: The Journal of Biological Databases and Curation,[42] Molecular and Cellular Proteomics,[citation needed] the Journal of Molecular Graphics and Modelling and the EMBnet.journal.[citation needed]

Awards and honours[edit]

Attwood held a Royal Society University Research Fellowship (URF) from 1993 to 2002.[1]


  1. ^ a b c Anon (2016). "Teresa Attwood Professor of Bioinformatics". manchester.ac.uk. Manchester. Archived from the original on 24 December 2016.
  2. ^ a b Attwood, Teresa K. (1984). Chromonic mesophases (PhD thesis). University of Leeds. OCLC 59334329.
  3. ^ Corpas, Manuel (2007). Folding patterns in protein sequences (PhD thesis). University of Manchester. doi:10.6084/m9.figshare.964811.v1.
  4. ^ Teresa Attwood at Library of Congress
  5. ^ 57193816586 Attwood, Teresa's publications indexed by the Scopus bibliographic database. (subscription required)
  6. ^ a b Terri Attwood's ORCID 0000-0003-2409-4235
  7. ^ Attwood, T. K.; Lydon, J. E. (1984). "Lyotropic Mesophase Formation by Anti-Asthmatic Drugs". Molecular Crystals and Liquid Crystals. 108 (3–4): 349. Bibcode:1984MCLC..108..349A. doi:10.1080/00268948408078686.
  8. ^ "Teresa K Attwood". biochem.ucl.ac.uk/bsm/dbbrowser.
  9. ^ Terri K. Attwood at DBLP Bibliography Server Edit this at Wikidata
  10. ^ Terri Attwood publications indexed by Google Scholar Edit this at Wikidata
  11. ^ Attwood, T. K.; Coletta, A.; Muirhead, G.; Pavlopoulou, A.; Philippou, P. B.; Popov, I.; Romá-Mateo, C.; Theodosiou, A.; Mitchell, A. L. (2012). "The PRINTS database: A fine-grained protein sequence annotation and analysis resource--its status in 2012". Database. 2012: bas019. doi:10.1093/database/bas019. PMC 3326521. PMID 22508994.
  12. ^ Attwood, T. K.; Croning, M. D.; Flower, D. R.; Lewis, A. P.; Mabey, J. E.; Scordis, P.; Selley, J. N.; Wright, W. (2000). "PRINTS-S: The database formerly known as PRINTS". Nucleic Acids Research. 28 (1): 225–227. doi:10.1093/nar/28.1.225. PMC 102408. PMID 10592232.
  13. ^ Attwood, T. K.; Bradley, P.; Flower, D. R.; Gaulton, A.; Maudling, N.; Mitchell, A. L.; Moulton, G.; Nordle, A.; Paine, K.; Taylor, P.; Uddin, A.; Zygouri, C. (2003). "PRINTS and its automatic supplement, prePRINTS". Nucleic Acids Research. 31 (1): 400–402. doi:10.1093/nar/gkg030. PMC 165477. PMID 12520033.
  14. ^ Apweiler, R.; Attwood, T. K.; Bairoch, A.; Bateman, A.; Birney, E.; Biswas, M.; Bucher, P.; Cerutti, L.; Corpet, F.; Croning, M. D.; Durbin, R.; Falquet, L.; Fleischmann, W.; Gouzy, J.; Hermjakob, H.; Hulo, N.; Jonassen, I.; Kahn, D.; Kanapin, A.; Karavidopoulou, Y.; Lopez, R.; Marx, B.; Mulder, N. J.; Oinn, T. M.; Pagni, M.; Servant, F.; Sigrist, C. J.; Zdobnov, E. M. (2001). "The InterPro database, an integrated documentation resource for protein families, domains and functional sites". Nucleic Acids Research. 29 (1): 37–40. doi:10.1093/nar/29.1.37. PMC 29841. PMID 11125043.
  15. ^ Apweiler, R.; Attwood, T. K.; Bairoch, A.; Bateman, A.; Birney, E.; Biswas, M.; Bucher, P.; Cerutti, L.; Corpet, F.; Croning, M. D. R.; Durbin, R.; Falquet, L.; Fleischmann, W.; Gouzy, J.; Hermjakob, H.; Hulo, N.; Jonassen, I.; Kahn, D.; Kanapin, A.; Karavidopoulou, Y.; Lopez, R.; Marx, B.; Mulder, N. J.; Oinn, T. M.; Pagni, M.; Servant, F.; Sigrist, C. J. A.; Zdobnov, E. M.; Interpro, C. (2000). "InterPro--an integrated documentation resource for protein families, domains and functional sites". Bioinformatics. 16 (12): 1145–1150. doi:10.1093/bioinformatics/16.12.1145. PMID 11159333.
  16. ^ a b http://www.biocurator.org/elec/candidates2011/Attwood.pdf Attwood biography from biocurator.org
  17. ^ "BioMinT: Biological Text Mining EU FP5 Quality of Life Project". Archived from the original on 19 June 2012.
  18. ^ "EMBER - European Multimedia Bioinformatics Educational Resource". www.bioinf.man.ac.uk.
  19. ^ "Platform grant: PARADIGM - Platform for Annotation, Robust Analysis, Data Integration & Genome Management". Retrieved 25 July 2012.
  20. ^ "COST Action: NGS-Data Analysis Network". Retrieved 25 July 2012.
  21. ^ "start – AllBio". Archived from the original on 29 December 2012.
  22. ^ Pettifer, S.; Ison, J.; Kalas, M.; Thorne, D.; McDermott, P.; Jonassen, I.; Liaquat, A.; Fernández, J. M.; Rodriguez, J. M.; Partners, I. -; Pisano, D. G.; Blanchet, C.; Uludag, M.; Rice, P.; Bartaseviciute, E.; Rapacki, K.; Hekkelman, M.; Sand, O.; Stockinger, H.; Clegg, A. B.; Bongcam-Rudloff, E.; Salzemann, J.; Breton, V.; Attwood, T. K.; Cameron, G.; Vriend, G. (2010). "The EMBRACE web service collection". Nucleic Acids Research. 38 (Web Server issue): W683–W688. doi:10.1093/nar/gkq297. PMC 2896104. PMID 20462862.
  23. ^ "European Kidney and Urine Proteomics | Eurokup". Retrieved 25 July 2012.
  24. ^ "Welcome to ELIXIR". Retrieved 26 July 2012.
  25. ^ "Committees | GOBLET". www.mygoblet.org. 16 November 2014. Retrieved 24 August 2016.
  26. ^ Corpas, M.; Jimenez, R. C.; Bongcam-Rudloff, E.; Budd, A.; Brazas, M. D.; Fernandes, P. L.; van Gelder, C.; Korpelainen, E.; Lewitter, F.; McGrath, A.; MacLean, D.; Palagi, P.; Rother, K.; Taylor, J.; Via, A.; Watson, M.; Schneider, M. V.; Attwood, T. K. (2015). "The GOBLET training portal: a global repository of bioinformatics training materials, courses and trainers". Bioinformatics. 31 (1): 140–142. doi:10.1093/bioinformatics/btu601. PMC 4271145. PMID 25189782.
  27. ^ Burge, S.; Attwood, T. K.; Bateman, A.; Berardini, T. Z.; Cherry, M.; O'Donovan, C.; Xenarios, L.; Gaudet, P. (2012). "Biocurators and Biocuration: Surveying the 21st century challenges". Database. 2012: bar059. doi:10.1093/database/bar059. PMC 3308150. PMID 22434828.
  28. ^ Lord, P. W.; Selley, J. N.; Attwood, T. K. (2002). "CINEMA-MX: A modular multiple alignment editor". Bioinformatics. 18 (10): 1402–1403. doi:10.1093/bioinformatics/18.10.1402. PMID 12376388.
  29. ^ Parry-Smith, D. J.; Payne, A. W. R.; Michie, A. D.; Attwood, T. K. (1998). "CINEMA—a novel Colour INteractive Editor for Multiple Alignments". Gene. 221 (1): GC57–GC63. doi:10.1016/S0378-1119(97)00650-1. PMID 9852962.
  30. ^ Attwood, T. K.; Kell, D. B.; McDermott, P.; Marsh, J.; Pettifer, S. R.; Thorne, D. (2010). "Utopia documents: Linking scholarly literature with research data". Bioinformatics. 26 (18): i568–i574. doi:10.1093/bioinformatics/btq383. PMC 2935404. PMID 20823323.
  31. ^ Pettifer, S. R.; Sinnott, J. R.; Attwood, T. K. (2004). "UTOPIA—User-Friendly Tools for Operating Informatics Applications". Comparative and Functional Genomics. 5 (1): 56–60. doi:10.1002/cfg.359. PMC 2447318. PMID 18629035.
  32. ^ Mitchell, A. L.; Reich, J. R.; Attwood, T. K. (2003). "PRECIS: Protein reports engineered from concise information in SWISS-PROT". Bioinformatics. 19 (13): 1664–1671. doi:10.1093/bioinformatics/btg204. PMID 12967963.
  33. ^ Mitchell, A. L.; Divoli, A.; Kim, J. -H.; Hilario, M.; Selimas, I.; Attwood, T. K. (2005). "METIS: Multiple extraction techniques for informative sentences". Bioinformatics. 21 (22): 4196–4197. doi:10.1093/bioinformatics/bti675. PMID 16159915.
  34. ^ Divoli, A.; Attwood, T. K. (2005). "BioIE: Extracting informative sentences from the biomedical literature". Bioinformatics. 21 (9): 2138–2139. doi:10.1093/bioinformatics/bti296. PMID 15691860.
  35. ^ Pettifer, S.; Thorne, D.; McDermott, P.; Marsh, J.; Villéger, A.; Kell, D. B.; Attwood, T. K. (2009). "Visualising biological data: A semantic approach to tool and database integration". BMC Bioinformatics. 10 (Suppl 6): S19. doi:10.1186/1471-2105-10-S6-S19. PMC 2697642. PMID 19534744.
  36. ^ Attwood, T. K.; Kell, D. B.; McDermott, P.; Marsh, J.; Pettifer, S. R.; Thorne, D. (2009). "Calling International Rescue: Knowledge lost in literature and data landslide!". Biochemical Journal. 424 (3): 317–333. doi:10.1042/BJ20091474. PMC 2805925. PMID 19929850.
  37. ^ Anon. "Grants awarded to Terri Attwood by the EPSRC". epsrc.ac.uk. Swindon. Retrieved 25 July 2012.
  38. ^ Parry-Smith, David J.; Attwood, Teresa K. (1999). Introduction to bioinformatics. New York: Longman. ISBN 978-0-582-32788-7.
  39. ^ Attwood, Teresa K.; Higgs, Paul (2005). Bioinformatics And Molecular Evolution. Cambridge, Massachusetts: Blackwell Publishers. ISBN 978-1-4051-0683-2.
  40. ^ Attwood, Teresa K.; Pettifer, Stephen Robert; Thorne, David (2016). Bioinformatics Challenges at the Interface of Biology and Computer Science: Mind the Gap. Chichester, West Sussex ; Hoboken, New Jersey: Wiley-Blackwell. p. 424. ISBN 9780470035481. OCLC 951190363.
  41. ^ "Biochemical Journal Editorial Board". Archived from the original on 20 February 1999. Retrieved 25 July 2012.
  42. ^ "Oxford Journals | Life Sciences | Database | Editorial board". Retrieved 25 July 2012.