Thiosulfate sulfurtransferase
| thiosulfate sulfurtransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.1.1 | ||||||||
| CAS no. | 9026-04-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a thiosulfate sulfurtransferase (EC 2.8.1.1) is an enzyme that catalyzes the chemical reaction
- thiosulfate + cyanide sulfite + thiocyanate
Thus, the two substrates of this enzyme are thiosulfate and cyanide, whereas its two products are sulfite and thiocyanate.
This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:cyanide sulfurtransferase. Other names in common use include thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, and rhodanase.
Structural studies
As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes 1BOH, 1BOI, 1DP2, 1E0C, 1H4K, 1H4M, 1ORB, 1RHD, 1RHS, 1UAR, and 2ORA.
References
- Sorbo BH; Lagerkvist, Ulf; Pesola, Rainer; Virtanen, Artturi I.; Sörensen, Nils Andreas (1953). "Crystalline rhodanese. I. Purification and physicochemical examination". Acta Chem. Scand. 7: 1129–1136. doi:10.3891/acta.chem.scand.07-1129.
- Sorbo BH; Lagerkvist, Ulf; Pesola, Rainer; Virtanen, Artturi I.; Sörensen, Nils Andreas (1953). "Crystalline rhodanese. II. The enzyme catalyzed reaction". Acta Chem. Scand. 7: 1137–1145. doi:10.3891/acta.chem.scand.07-1137.
- Westley J; Green JR (1959). "Crystalline beef kidney rhodanese". J. Biol. Chem. 234: 2325–6. PMID 13844173.
- Thiosulfate+Sulfurtransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)