Tuber cinereum

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Not to be confused with tuberculum cinereum, ala cinerea (vagal trigone) or tuber cinereum (fungus).
Tuber cinereum
Base of brain (Tuber cinerum visible at center).
Latin Tuber cinereum
Gray's p.813
MeSH A08.186.211.730.385.357.352.870
NeuroNames hier-376
NeuroLex ID Tuber cinereum
TA A14.1.08.408
FMA 62327
Anatomical terms of neuroanatomy

The tuber cinereum is a hollow eminence of gray matter situated between the mammillary bodies and the optic chiasm. The tuber cinereum is part of the hypothalamus.


Laterally it is continuous with the anterior perforated substances and anteriorly with a thin lamina, the lamina terminalis.

The infundibulum, a hollow conical process, projects from the tuber cinereum. The infundibulum extends forward and down where it is attached to the posterior lobe of the pituitary gland.

It houses the nuclei:

  • tuberal nucleus
  • tuberomammillary nucleus[1]

Tuberomammillary nucleus[edit]

The tuberomammillary nucleus (TMN) is the sole source of histamine in the brain.[2]


Circadian rhythm[edit]

By its release of histamine, the tuberomammillary nucleus of the tuber cinereum helps to regulate the circadian cycle.

Additional images[edit]

See also[edit]


This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

  1. ^ - Abstracts for References 5 and 6 of 'Hypothalamic-pituitary axis'
  2. ^ - IngentaConnect Estrogen receptors and metabolic activity in the ...

External links[edit]