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User:Ppgardne/Hfq binding sRNA

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A Hfq binding sRNA is a sRNA that binds the bacterial RNA binding protein called Hfq. A number of bacterial small RNAs which have been shown to bind to Hfq have been characterised (see table). Many of these RNAs share a similar structure composed of three stem-loops. [1] Recent studies have expanded this list and experimentally validated a total of 64 Hfq binding sRNA in S. typhimurium.[2] [3][4]

Bacterial Hfq binding sRNAs
Family Family
RydC RNA Qrr RNA
OxyS RNA Spot 42 RNA
RyeB RNA CyaR RNA
RyhB RNA DicF RNA
GcvB RNA MicF RNA
MicC RNA RprA RNA
DsrA RNA MicA RNA / SraD RNA
SraE RNA / OmrB RNA / RygB RNA SraJ RNA
SraH RNA GadY RNA
SgrS RNA SroC RNA
RybB RNA RybB
RyeF MicA
OmrA RNA / RygA RNA

References

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  1. ^ Zhang A, Wassarman KM, Rosenow C, Tjaden BC, Storz G, Gottesman S (2003). "Global analysis of small RNA and mRNA targets of Hfq". Mol. Microbiol. 50 (4): 1111–24. doi:10.1046/j.1365-2958.2003.03734.x. PMID 14622403.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Pfeiffer V, Sittka A, Tomer R, Tedin K, Brinkmann V, Vogel J (December 2007). "A small non-coding RNA of the invasion gene island (SPI-1) represses outer membrane protein synthesis from the Salmonella core genome". Molecular Microbiology. 66 (5): 1174–91. doi:10.1111/j.1365-2958.2007.05991.x. PMID 17971080.{{cite journal}}: CS1 maint: date and year (link) CS1 maint: multiple names: authors list (link)
  3. ^ Sittka A, Lucchini S, Papenfort K; et al. (2008). "Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq". PLOS Genetics. 4 (8): e1000163. doi:10.1371/journal.pgen.1000163. PMC 2515195. PMID 18725932. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
  4. ^ Padalon-Brauch G, Hershberg R, Elgrably-Weiss M; et al. (April 2008). "Small RNAs encoded within genetic islands of Salmonella typhimurium show host-induced expression and role in virulence". Nucleic Acids Research. 36 (6): 1913–27. doi:10.1093/nar/gkn050. PMC 2330248. PMID 18267966. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: date and year (link) CS1 maint: multiple names: authors list (link)

Category:Non-coding RNA