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Chenodeoxycholoyltaurine hydrolase

From Wikipedia, the free encyclopedia
chenodeoxycholoyltaurine hydrolase
Identifiers
EC no.3.5.1.74
CAS no.125752-75-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a chenodeoxycholoyltaurine hydrolase (EC 3.5.1.74) is an enzyme that catalyzes the chemical reaction

chenodeoxycholoyltaurine + H2O chenodeoxycholate + taurine

Thus, the two substrates of this enzyme are chenodeoxycholoyltaurine and H2O, whereas its two products are chenodeoxycholate and taurine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chenodeoxycholoyltaurine amidohydrolase. This enzyme participates in bile acid biosynthesis.

References

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  • Kawamoto K, Horibe I, Uchida K (December 1989). "Purification and characterization of a new hydrolase for conjugated bile acids, chenodeoxycholyltaurine hydrolase, from Bacteroides vulgatus". J. Biochem. 106 (6). Tokyo: 1049–53. PMID 2628421.