Helper virus

A helper virus is a virus that allows an otherwise-deficient coinfecting virus to replicate. These can be naturally occurring as with Hepatitis D virus, which requires Hepatitis B virus to coinfect cells in order to replicate. Helper viruses are also commonly used to replicate and spread viral vectors for gene expression and gene therapy.^[1]

References

^ Graham BS, Crowe JE, Ledgerwood JE (2007). "14 - Immunization Against Viral Diseases". In Knipe DM, Howley PM (eds.). Fields Virology (6 ed.). Wolters Kluwer Health. p. 403.

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[1] Graham BS, Crowe JE, Ledgerwood JE (2007). "14 - Immunization Against Viral Diseases". In Knipe DM, Howley PM (eds.). Fields Virology (6 ed.). Wolters Kluwer Health. p. 403.

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v t e Microbiology: Virus
History Introduction Social history of viruses Virology
Components	Capsid Viral envelope Viral protein
Viral life cycle	Viral entry Viral replication Viral shedding Viroplasm Virus latency Lytic cycle Lysogenic cycle
Genetics	Antigenic drift Antigenic shift Phenotype mixing Reassortment Viral evolution
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References