Jump to content

Albinism

From Wikipedia, the free encyclopedia
(Redirected from Animal with albinism)
"Albino" redirects here. For other uses, see Albino (disambiguation).
This article is about the biological term. For the medical condition in humans, see Albinism in humans.

"Claude", an albino American alligator at the California Academy of Sciences
American alligator with normal pigmentation
Examples of albino laboratory mammals
Mice with Type I oculocutaneous albinism
Rat with Type I oculocutaneous albinism

Albinism is the congenital absence of melanin in an animal or plant resulting in white hair, feathers, scales and skin and reddish pink or blue eyes.[1][2] Individuals with the condition are referred to as albinos.

Varied use and interpretation of the terms mean that written reports of albinistic animals can be difficult to verify. Albinism can reduce the survivability of an animal; for example, it has been suggested that albino alligators have an average survival span of only 24 hours due to the lack of protection from UV radiation and their lack of camouflage to avoid predators.[3] It is a common misconception that all albino animals have characteristic pink or red eyes (resulting from the lack of pigment in the iris allowing the blood vessels of the retina to be visible); this is not the case for some forms of albinism.[4] Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally occurring albino animals exist in the wild, e.g., Mexican cave tetra. Albinism is a well-recognized phenomenon in molluscs, both in the shell and in the soft parts. It has been claimed by some e.g., [5] that albinism can occur for a number of reasons aside from inheritance, including genetic mutations, diet, living conditions, age, disease, or injury. However, this is contrary to definitions where the condition is inherited.

Oculocutaneous albinism (OCA) is a clearly defined set of seven types of genetic mutations which reduce or completely prevent the synthesis of eumelanin or pheomelanin, resulting in reduced pigmentation.[6] Type I oculocutaneous albinism (OCA1a) is the form most commonly recognised as 'albino' as this results in a complete absence of melanin in the skin, hair/fur/feathers, and pink pupils, however this has led many to assume that all albinos are pure white with pink pupils, which is not the case.[7][8][6]

In plants, albinism is characterised by partial or complete loss of chlorophyll pigments and incomplete differentiation of chloroplast membranes. Albinism in plants interferes with photosynthesis, which can reduce survivability.[9] Some plant variations may have white flowers or other parts. However, these plants are not totally devoid of chlorophyll. Terms associated with this phenomenon are "hypochromia" and "albiflora".[10]

Biological colouration

[edit]

Biological pigments are substances produced by living organisms that have a colour resulting from selective colour absorption. What is perceived as a plant or animal's "colour" is the wavelengths of light that are not absorbed by the pigment, but instead are reflected. Biological pigments include plant pigments and flower pigments.

Animal colouration

[edit]
Main article: Animal coloration

Animals can appear coloured due to two mechanisms, pigments and structural colours. Animals may have both biological pigments and structural colours, for example, some butterflies with white wings.

Pigments

[edit]

Many animal body-parts, such as skin, eyes, feathers, fur, hair, scales and cuticles, contain pigments in specialized cells called chromatophores. These cells are found in a wide range of animals including amphibians, fish, reptiles, crustaceans and cephalopods. Mammals and birds, in contrast, have a class of cells called melanocytes for colouration. The term chromatophore can also refer to coloured, membrane-associated vesicles found in some forms of photosynthetic bacteria. Chromatophores are largely responsible for generating skin and eye colour in poikilothermic animals and are generated in the neural crest during embryonic development. Mature chromatophores are grouped into subclasses based on their colour under white light:

Structural colours

[edit]

Animals can also appear coloured due to structural colour, the result of coherent scattering[11] perceived as iridescence. The structures themselves are colourless. Light typically passes through multiple layers and is reflected more than once. The multiple reflections compound one another and intensify the colours. Structural colour differs according to the observer's position whereas pigments appear the same regardless of the angle-of-view. Animals that show iridescence include mother of pearl seashells, fish, and peacocks. These are just a few examples of animals with this quality, but it is most pronounced in the butterfly family.

  • iridophores (reflective/iridescent): sometimes called "guanophores", reflect light using plates of crystalline chemochromes made from guanine[12]
  • leucophores (reflective white): found in some fish, utilize crystalline purines (often guanine) to produce a reflective, shiny, white colour.

Plant colouration

[edit]

The primary function of pigments in plants is photosynthesis, which uses the green pigment chlorophyll along with several red and yellow pigments including porphyrins, carotenoids, anthocyanins and betalains.

Definition

[edit]
Albino wallaby (OCA1a) with her offspring

Definitions of albinism vary and are inconsistent. While they are clear and precise for humans and other mammals, this is because the majority of mammals have only one pigment, melanin. Many animals have pigments other than melanin, and some also have structural colours. Some definitions of albinism, whilst taking most taxa into account, ignore others. So, "a person or animal with very pale skin, white hair or fur, and pink eyes caused by a medical condition that they were born with"[13] and "a person or animal with white skin and hair and pink eyes"[14] do not include feathers, scales or cuticles of birds, fish and invertebrates, nor do they include plants. Some definitions are too broad to be of much use, e.g. "an animal or plant with a marked deficiency in pigmentation".[15]

Other definitions of albinism encompass most of the major animal taxa, but ignore the several other pigments that non-mammalian animals have and also structural colouration. For example, "Absence of the pigment melanin in the eyes, skin, hair, scales, or feathers."[16] refers only to the pigment melanin.

Because of the various uses of different terms applied to colouration, some authors have indicated that the colour of the eyes is the defining characteristic of albinism, e.g. "This leads to a good diagnostic feature with which to distinguish leucistic and albino individuals – the colour of the eye."[17] However, there are multiple forms of albinism – currently seven types recognised for humans – most of which do not result in red or pink pupils.[4]

The term "partial albino" is sometimes used in the literature. However, it has been stated that "A common misnomer is 'partial albino' – this is not possible since albinism affects the whole plumage of a bird, not just part"[17] and the definition of albinism precludes the possibility of "partial albinism" in which a mostly white bird shows some form of melanin pigmentation. "It is simply impossible, just like being 'partially pregnant' ".[18] Conditions that are commonly termed "partial albino" include neural crest disorders such as piebaldism, Waardenburg syndrome, or other depigmentation conditions such as vitiligo. These conditions result from fundamentally different causes to the seven types of oculocutaneous albinism that have been identified in humans (and confirmed in some other animals) and the use of the term "partial albino" is therefore misleading.[6]

One definition states that "albinism, (from the Latin albus, meaning "white"), hereditary condition characterized by the absence of pigment in the eyes, skin, hair, scales, or feathers",[19] however, this does not encompass invertebrates, nor does it include plants. Furthermore, it could be interpreted that "...absence of pigment..." does not include an absence of structural colours.

The lack of clarity about the term is furthered when the name of an animal includes the term "albino" although the animals (clearly) do not have the condition. For example, the albino gaur has this name because it is ash-grey whereas other gaur are almost black.

A clear definition appears to be – "Congenital absence of any pigmentation or colouration in a person, animal, or plant, resulting in white hair and pink eyes in mammals."[2] Whilst this does not state specifically that non-mammalian albino animals (or plants) are white, this can be inferred from "...absence of any pigmentation or colouration..." Due to the varied use and interpretation of the term "albino", written reports of albinistic organisms can often not be verified.

Mechanism and frequency

[edit]
A hedgehog with albinism due to a genetic mutation

Melanin is an organic pigment that produces most of the colour seen in mammals. Depending on how it is created, melanin comes in two colour ranges, eumelanin (producing dark browns and blacks) and pheomelanin (producing light reddish tans and blondes). The dark and light melanins have their influence either alone or in conjunction, making either plain or multi-coloured coats. Sometimes, in a condition called agouti, they make multi-coloured individual hairs. The production of melanin occurs in melanocytes in a complex process involving the enzyme tyrosinase. Mammals have a gene that codes for the presence of tyrosinase in cells – called the TYR gene. If this gene is altered or damaged, melanin cannot be reliably produced and the mammal becomes an albino. Besides the TYR gene, several other genes can cause albinism. This is because other hormones and proteins are involved in melanin production, the presence of which is genetically determined. In mice, a total of 100 genes are known to affect albinism.[20]

Most forms of albinism follow a recessive pattern of inheritance.[21] However, this is not always the case. In palomino horses, genes coding for coat whiteness are dominant, and this is also true for several arctic mammals who possess dominant white colors which are pseudo-albinistic. However, these mammals differ from truly recessive albinos in that they still produce tyrosinase, and have normal eye pigmentation.[22] In Japan, research has identified a dominant albinism in the rainbow trout.[23][24]

Albinism occurs throughout the animal kingdom. The condition is most commonly seen in birds, reptiles and amphibians, but more rarely seen in mammals and other taxa. It is often difficult to explain occasional occurrences, especially when only one documented incidence has occurred, such as only one albino gorilla and one albino koala.[25] In mammals, albinism occurs once in every 10,000 births, but in birds, the rate is once in every 1,764 births.[26]

Some species, such as white peacocks, swans and geese, are not believed to be true albinos, as they do not have red eyes, rather, their colouration is suggested to be the expression of a white fur or feather gene, not a lack of melanin.[27]

Consequences

[edit]

Melanin has several functions in most mammals and other animals; these are disrupted by albinism.

Abnormal eye development and appearance

[edit]

Melanin functions in the normal development of various parts of the eye, including the iris, retina, eye muscles, and optic nerve. The absence of melanin results in abnormal development of eyes and leads to problems with focusing, and depth perception. The eyes of albino animals appear red because the colour of the red blood cells in the retina can be seen through the iris, which has no pigment to obscure this. Some albino animals may have pale-blue eyes due to other colour generating processes. Albino vertebrates exposed to intense light typically lose photoreceptors due to apoptosis.[28]

A true albino squirrel. Note the reddish-pink eyes.

In all albino mammals studied, the centre of the retina is under-developed and there is a deficit of rod cells, which detect light levels; the central ganglion cell density is approximately 25% below normal (except for the eastern gray squirrel). In nearly all mammals, the overwhelming majority of photoreceptors are rods rather than cones, which detect color. Albinism specifically affects the rod cells, but the number and distribution of the cones is unaffected. In contrast, the retinas of birds are cone rich, meaning that the vision of albino birds is affected less than albino mammals.[29]

Reduced protection from sunlight in albino creatures

[edit]

Melanin protects the skin from ultra-violet radiation in sunlight. Melanosomes block harmful electromagnetic radiation from the sun while allowing beneficial frequencies to enter the body. This means some animals may die from UV radiation due to a lack of protection. Albino humans must use an excessive amount of sunscreen, even if the sun is hidden behind the clouds.

Survival value

[edit]

Animals with albinism may lack protective camouflage in some environments, and are therefore less able to conceal themselves from their predators or prey. However, in other environments albino animals are less likely to be killed, and selection may favor them.[30] The lower survival rate of animals with albinism in certain environments has been documented,[31][32] however, it has been stated that in studies where animals had many places to hide, predators captured albino and normally coloured animals at the same rate.[20] Furthermore, in certain species, albino animals may be excluded from families or other groups,[26] or rejected as mates.[20] On the other hand, there is also evidence for positive selection for albinism in some animals,[33] as well as cultural selection favoring albino people in some human societies, which results in the increase of genes associated with albinism.[34] The founder effect may explain why some animal populations become selected for albinism.[35]

The novelty of albino animals has occasionally led to their protection by groups such as the Albino Squirrel Preservation Society. They have also been protected in studies on their ecology, sociology and behaviour.[36]

Reduced viability

[edit]

Studies on medaka fish in the laboratory, i.e. with no predators, sufficient food supply, controlled temperatures, etc., found that albinos had considerably reduced viability; from 800 albino embryos, only 29 survived to full adulthood.[37] Early studies on fish led some researchers to describe albinism as a "semi-lethal mutation".[37]

Hearing disorders

[edit]

Pigmentation disorders such as albinism are occasionally associated with hearing impairments in mice, rats, guinea pigs and cats.[38]

In mammals

[edit]

Artificially selected

[edit]
Examples of pet mammals artificially selected for albinism
Albino ferret
Albino rabbit

Intentionally bred albinistic strains of some animal species are commonly used as model organisms in biomedical research and also as pets. Examples include the BALB/c mouse and Wistar and Sprague Dawley rat strains, laboratory rabbits and ferrets.[39] Some researchers have argued that albino animals are not always the best choice for scientific studies due to the consequences of albinism (e.g. hearing and visual impairments).[40]

Many individual albino mammals are in captivity and were caught while young. However, the survival prospects of these creatures into adulthood outside of captivity are uncertain.[citation needed] It is doubtful whether these individuals would have survived to become adults without the protection and care they receive in captivity.[41]

Naturally occurring

[edit]
"Snowflake", a blue-eyed western lowland gorilla caught in the wild with Type IV oculocutaneous albinism

It has been claimed that "Squirrels are the only known albino mammal to survive successfully in the wild".[29] The retina of the squirrel (Sciurus carolinensis) is unusual for mammals as it is rich in cones. Central cell densities are less than 5% lower in albino squirrels than in pigmented individuals. This relatively minor disruption to vision is thought to assist in the survivability of albino squirrels in the wild. This is supported by observations that the behaviour of albinos in the wild, e.g. leaping from branch to branch, is similar to pigmented squirrels.[29]

A 2012 survey of the literature reported that in India, there were several records of albino mammals including the tiger, lesser mouse-tailed bat, chital, common palm civet, northern palm squirrel, five-striped palm squirrel and wild boar.[42]

Albino macaques have been reported in several occasions including a toque macaque (M. sinica), rhesus macaque (M. mulatta), and bonnet macaque (M. radiata).[42]

Albinism was observed in jungle cats (Felis chaus) and jackals (Canis aureus) along the coastline of the southern Western Ghats (Kerala and Kanyakumari coast, India). Albinism was observed in jungle cats from the Amaravila area of Trivandrum district in the Kerala State. Albinism in jackals was observed from the Polooni area in Malappuram district and Chaliyam area of Calicut district (Kerala). As albinism is observed in those areas where the density of these mammals is comparatively low, it is concluded that continuous inbreeding could be the reason for expression of albinism.[43]

A study on albinistic prairie voles (Microtus ochrogaster) found that albinism in this species conferred an advantage for the males compared to the wild-type; albino males had higher mount frequencies than wild-type males. In addition, the albinos had greater differential fertilizing capacity.[44]

Albinism can also occur in marsupials and monotremes, such as echidnas, kangaroos, koalas, possums, wallabies and wombats.

Marine mammals

[edit]
An albino killer whale

The costs of albinism for marine mammals may include reduced heat absorption in colder waters, poor camouflage from predators, increased sensitivity to sunlight, and impaired visual communication. Despite the costs, some individuals do reach adult age and breeding status.[45]

Albino dolphins were first sighted in the Gulf of Mexico in 1962. Since 1994, three further individuals have been seen. These tend to be pink in colour due to blood vessels showing through the blubber and unpigmented skin.

A report published in 2008 stated that in marine mammals, "anomalously white" individuals have been reported for 21 cetacean species and seven pinniped species but there were no known reports of anomalously white sea otters (Enhydra lutris) or sirenians.[45]

Whales and dolphins also may appear white if extensively scarred, or covered with a fungus, such as Lacazia loboi.[45]

Famous albino mammals

[edit]

Famous albino mammals include Migaloo, a humpback whale living off the coast of Australia; Pinky, a bottlenose dolphin living in and around in Calcasieu Lake, Louisiana; Carolina Snowball, a popular albino bottlenose dolphin displayed at the Miami Seaquarium in the early 1960s; Snowflake, a Barcelona Zoo gorilla, and Mahpiya Ska, (Sioux for White Cloud), a buffalo in Jamestown, North Dakota,[46][47] and inspiration for Herman Melville's novel Moby-Dick, a sperm whale known as Mocha Dick.

In birds

[edit]
Kookaburras
Albino kookaburra
Blue winged kookaburra with normal pigmentation

The most important pigments that determine plumage colouration in birds are melanines and carotenoids. The latter are ingested in food and transformed into colour pigments by enzymes. Aberrations in this pigmentation are mostly caused by food deficiencies and usually do not have a genetic basis. Well-known examples are flamingos, which owe their distinct pink colour to the presence of red carotenoids in their natural food. When these carotenoids are in short supply, these birds appear white after the next moult. Mutations causing changes in carotenoid-based colour pigments are rare; melanine mutations occur much more frequently. Two types of melanin, eumelanin and phaeomelanin, are present in birds. In the skin and eyes, only eumelanin is present. In some bird species, the colour is completely caused by eumelanin, however, both types of melanin are found in most species. In birds, albinism has been defined as "a total lack of both melanins in feathers, eyes and skin as a result of an inherited absence of tyrosinase",[18] however, this ignores the effects of other pigments and structural colours.

An albino bird has a white beak, white plumage, non-coloured skin, white talons and pink or red eyes. Albinism is only seen in about 1 of every 1,800 birds. The two most common species of albino birds are the common house martin and the American robin.[25] Famous albino birds include "Snowdrop", a Bristol Zoo penguin.[48]

In one study, albinism in birds has been categorised according to the extent of pigment absence.[49]

  1. Total albinism – a simultaneous complete absence of melanin from the eyes, skin, and feathers. This is the rarest form. Only 7% of 1,847 cases of avian albinism examined was this type.
  2. Incomplete albinism – when melanin is not simultaneously absent from the eyes, skin and feathers.
  3. Imperfect albinism – when melanin is reduced in the eyes, skin and feathers.
  4. Partial albinism – when albinism is localized to certain areas of the body.

However, it has been argued that the definition of albinism precludes the possibility of "partial albinism" in which a mostly white bird shows some form of melanin pigmentation. "It is simply impossible, just like being 'partially pregnant'.[18]

In fish

[edit]

As with other animals, it has been stated that for fish to be properly described as "albino", they must have a white body and pink or red eyes.[37]

Artificially selected

[edit]
Examples of fish artificially selected for albinism
Albino catfish
Albino peacock cichlid
Albino giant gourami

Zebrafish have three types of chromatophores—iridophores, melanophores, and xanthophores—which produce silver, black, and yellow pigmentation respectively. Zebrafish that lack iridophores are known as roy mutants, those that lack melanophores as albino mutants, and those which lack both melanophores and iridophores are ruby mutants. The gross eye morphology, feeding and swimming behaviours between wild-type and albino zebrafish were indistinguishable, except under dim or bright light or low contrast.[50] In mammals, albinism is occasionally associated with hearing impairments. However, when tested, there was no differences in responses between wild-type and albinistic European wels catfish (Silurus glanis) and South American bronze catfish (Corydoras aeneus). Similarly, Mexican blind cave fish (Astyanax mexicanus) do not differ in hearing sensitivity from the normally pigmented and eyed surface-dwelling populations. Fish lack melanin in the inner ear, meaning that hearing in fishes is less likely to be affected by albinism than in mammals.[38]

Naturally occurring

[edit]

There are several reports of total albinism in both freshwater and marine fish, however, frequently captured albino fish are only reported in aquarium magazines and local newspapers.[51]

The incidence of albinism can be artificially increased in fish by exposing the eggs to heavy metals (e.g. arsenic, cadmium, copper, mercury, selenium, zinc).[52]

In the wild, albinism is reasonably common in the teleosts, especially the Pleuronectiformes (flatfish), however, it is rarely reported in the elasmobranchs.[53] Albinism has been reported in hagfish, lampreys, sharks, rays and numerous teleost fishes, e.g. catfishes, grunts or cyprinids.[38]

In Actinopterygii

[edit]

Albino and normally pigmented channel catfish (Ictalurus punctatus) differ in their characteristics. Normal individuals of this species are superior to albinos in body weight and total length. Albinos crossed with other albinos require 11 days longer to spawn and produce smaller egg masses. These masses contain eggs of lighter weight with poorer hatchability than crosses of normal fish. The albino fish have lower survival rates than normal fish but dress-out percentages are nearly equal.[54]

Some wild cave fish have populations that are albinistic. The Mexican cave tetra is a species that has evolved specialized characteristics in a series of independent caves. One of these is albinism linked to the Oca2 gene, a known pigmentation gene. This trait has evolved independently in at least two caves.[55]

In Chondrichthyes

[edit]

In the class Chondrichthyes, several species of naturally occurring albino rays and sharks have been recorded. Furthermore, an albino individual spotted ratfish (Hydrolagus colliei) from the order Chimaeriformes has been reported.[56]

Albinistic individuals of the following shark species have been reported:[57][58][59]

A study published in 2006 reported albinistic individuals of the following ray species:[58]

In Hyperoartia

[edit]

There are several reports of albino lampreys and it has been estimated that this occurs at a frequency of one in 100,000 normal individuals.[37]

In Sarcopterygii

[edit]

Albinism in the African lungfish has been reported on at least two occasions.[60]

In reptiles

[edit]
"Albino" California kingsnake

Many reptiles labeled as albino are, in fact, not completely lacking in all colour pigments. They are actually amelanistic, not albino. Reptiles often possess at least two pigments. Among the most common are xanthin (yellow) and erythrin (red). An amelanistic reptile therefore, may still have pale yellow, orange, or red pigmentation.

The California Academy of Science, in the Steinhart Aquarium, as of 2015, has on display an albino American alligator named "Claude". The alligator is partially blind because of lack of pigment in its eyes.[61] The albino alligator hatched from the egg in 1995 in Florida, and was brought to the academy in 2008. This alligator would not have survived in the wild because its whiteness would have made it too easy a prey object. The only known albino alligators are in captivity.[62] While extremely rare, white-coloured crocodiles and alligators do exist in other places. However, most of these animals are leucistic given that they have a general loss of pigmentation with some colour tinges remaining on their bodies although looking at first like other albino creatures, thus creating the misconception that the reptiles are albino themselves when they are not. Four such alligators are kept at the Gatorland theme park in the U.S. state of Florida.[63] In Australia, a crocodile believed to be "part-albino" and nicknamed by people in the area as "Michael Jackson", attacked and killed a man.[64]

In snakes, partial absence of pigment is more common than absolute albinism. For snakes that are usually patterned in colours, they appear as a faint blue, peach or yellowish. In these cases, there has been a genetic mutation in the melanin and pigment delivery. The appearance comes from the inability for full colours to be present, such as black, red, brown and others. The eyes of an albino snake are typically red or pink. Albino snakes can remain in the sunlight for several hours with minimal harm. Corn snakes and snakes of larger types, such as a boa or diamondback snakes, are the most commonly affected by albinism often appearing to be a pinkish or yellowish colour.[25]

Albino tortoises and turtles are uncommon; Sulcata tortoises are the most likely type of turtle to express albinism. The shells have an almost yellow colouration and they have pink eyes. For turtles, a pure white colour is nearly impossible, even with albinism. Albino turtles can have a longer lifespan than many other albino animals; their hard shells help to prevent predation and other environmental challenges. Vision and sensory organs are slightly affected.[25]

In 2012, an albino anole was reported and photographed.[65] In 2007, it was reported that an albino stumpy-tail lizard (possibly a shingleback lizard), approximately 12 cm (4.7 in) long and roughly 1 year old, had been found in Victoria, Australia.[66]

There are three known "albino" strains of leopard gecko, however, breeders state that albinos are generally recognized by their lack of black pigment and having red eyes is not a requirement to be considered an albino. These three strains are called "tremper albinos", "rainwater albinos" and "bell albinos".[67]

In amphibians

[edit]

As with reptiles, many amphibians labeled as albino are, in fact, not completely lacking in all colour pigments. They are actually amelanistic, not albino. Amphibians have six types of chromatophore in their skin, i.e. melanophores, xanthophores, erythrophores, leucophores, cyanophores and iridophores.[68] An amelanistic amphibian therefore, may still have various pigmentation.

Wood Frog with albino phenotype

The incidence of albinism in frogs, salamanders, and newts is relatively higher than other taxa. It has been estimated that one in four hundred of these animals is albino. When albino tadpoles hatch, they are almost transparent. This may help camouflage them initially, however, after two weeks, when their hindlegs begin to emerge, they become milky white. A survey in 2001 found hundreds of tiny albino plains leopard frogs, but when the researcher returned a few months later, not a single albino adult could be found.[39]

In European Salamandridae, albinism has been recorded in the fire salamander (Salamandra salamandra), gold-striped salamander (Chioglossa lusitanica), Italian crested newt (Triturus carnifex), marbled newt (Triturus marmoratus), Iberian ribbed newt (Pleurodeles waltl), alpine newt (Ichthyosaura alpestris) and two sub-species of the smooth newt (Lissotriton vulgaris vulgaris and Lissotriton vulgaris meridionalis).[68]

Genetics

[edit]

Genetic studies of albinism in amphibians have focused on mutations in the tyrosinase gene. The albino phenotype of the leopard frog (Rana pipiens) has been attributed to a failure in post-translational control in a single recessive tyrosinase gene which still has some tyrosinase and DOPA oxidase activity. This is in contrast with mammals, some of which have mutations that show no tyrosinase or DOPA oxidase activity in albinos.[69] The albino phenotype of the pond frog (Pelophylax nigromaculatus) has been attributed to one of three mutations that created a dysfunctional tyrosinase. Two of those mutations involve an insertion of a thymine (T), a frameshift mutation, resulting in a truncated isoform of the TYR protein that is defective. The other mutation involves the deletion of a codon, three nucleotides that code for a lysine (Lys). In the wrinkled frog (Glandirana rugosa) and in the rice frog (Fejervarya kawamurai), a substitution from a guanine (G) to an adenine (A) creates a missense mutation, in which a glycine (Gly) changes to an aspartic acid (Asp) and an arginine (Arg), respectively. These changes in the polypeptide chain causes a dysfunctional tyrosinase.[70]

Albino axolotl (an amphibian) are also used widely in the laboratory as their transparent skin allows observation of the underlying tissues during limb regeneration.

In invertebrates

[edit]

Albinism in molluscs has been recognized to be a hereditary phenomenon at least since 1900.[71] Albinism in molluscs can exist to a variable degree. Sometimes an individual snail has a normally pigmented body, but the shell is completely without the normal pigmentation because of a defect in the cells of the mantle. Shells of certain mollusc species can be translucent when they lack the normal pigmentation.[72]

In insects

[edit]

The neurohormone [His7]-corazonin induces darkening of the cuticle of Locusta migratoria. The Okinawa strain of this species is deficient in [His7]-corazonin and is albino. One of the typical features of Locusta migratoria is that they are gregarious locusts. However, the albino strain shows more solitarious behaviour.[73]

The yellow mutation in fruit flies is a mutation causing a congenital lack of normal pigment; it is a similar phenomenon to albinism in other organisms.[74]

In echinoderms

[edit]

The Japanese sea cucumber (Apostichopus japonicus) is an echinoderm that is caught in the wild or cultivated for food. Normal Japanese sea cucumbers start to develop pigmentation when they are about 1 cm long. The upperside becomes a dull, yellowish -brown to maroon and the underside a light brown. The body walls of adult, albino Japanese sea cucumbers contain only 0.24% melanin compared to 3.12% in normal adults. The difference in melanin content becomes visually apparent at 60 days of age. The epidermis is thinner in the albinos and contains fewer melanocytes. Albino individuals are similar to normal individuals in growth rate, digestion rate and fertility.[75]

Astaxanthin is the main carotenoid in marine crustaceans (and fish). It has been shown that adding astaxanthin to the feed can improve the skin and muscle colour of marine organisms and thereby increase their commercial and ornamental value.[75]

In arachnids

[edit]

"Depigmented" arthropods have been found, usually in cave populations.[76] "Albino" individuals of normally red citrus red mites (Panonychus citri) occasionally appear in laboratory colonies, however, these still contain green and yellow pigments. This albinism does not affect mortality.[77]

[edit]

In some animals, albinism-like conditions may affect other pigments or pigment-production mechanisms:

  • "Whiteface", a condition that affects some parrot species, is caused by a lack of psittacins.[78]
    A leucistic alligator at the Audubon Aquarium of the Americas, New Orleans, Louisiana
  • Axanthism is a condition common in reptiles and amphibians, in which xanthophore metabolism is affected rather than synthesis of melanin, resulting in reduction or absence of red and yellow pteridine pigments.[79]
  • Leucism differs from albinism in that the melanin is, at least, partially absent but the eyes retain their usual colour. Some leucistic animals are white or pale because of chromatophore (pigment cell) defects, and do not lack melanin.
  • Melanism is the direct opposite of albinism. An unusually high level of melanin pigmentation (and sometimes absence of other types of pigment in species that have more than one) results in an appearance darker than non-melanistic specimens from the same gene pool.[80]

In plants

[edit]
An albino Rebutia seedling. The two seedlings are of the same age, but the albino stopped developing once the seed's reserve was exhausted.
The foliage of an Albino redwood. Note the distinctive white coloration of the needles.

In plants, albinism is characterised by partial or complete loss of chlorophyll pigments and incomplete differentiation of chloroplast membranes. Albinism in plants interferes with photosynthesis, which can reduce survivability.[9] Some plant variations may have white flowers or other parts. However, these plants are not totally devoid of chlorophyll. Terms associated with this phenomenon are "hypochromia" and "albiflora".[10]

Plants that are pale simply from being in the dark are termed etiolated.

Albino redwoods are rare examples of an albino tree with white needles; despite its lack of chlorophyll, it may grow to substantial size as a parasite, usually on the base of the (normal) redwood tree from which it first grew.[81][82][83] Only about sixty examples of albino redwoods are known.[82] Additionally, an even smaller number of "chimeric" redwood trees have both normal and white needles.

Albinism has frequently occurred in progeny of Black Tartarian, Bing and Hedelfingen varieties of sweet cherry.[84]

Some herbicides (e.g. glyphosate and triazines) can cause partial chlorosis in plants, even several seasons or years after applicating.[85]

In human culture

[edit]

The Albino Squirrel Preservation Society was founded at the University of Texas at Austin in 2001. Members of the society at the University of North Texas petitioned for an election to name their albino squirrel as the university's secondary mascot. The University of Louisville in Kentucky also has a documented population of albino squirrels.[86][unreliable source]

Albino animals are often kept as pets, for example, African clawed frog, guinea pigs and peacocks.[87][unreliable source]

See also

[edit]
Wikimedia Commons has media related to Albinism.

References

[edit]
  1. ^ Oetting, William S; Adams, David (2018). "Albinism: Genetics". eLS: 1–8. doi:10.1002/9780470015902.a0006081.pub3. ISBN 9780470016176. S2CID 239781411 – via John Wiley & Sons, Ltd.
  2. ^ a b "Albinism". The Free Dictionary. Retrieved January 31, 2015.
  3. ^ "New Albino Alligators". GeorgiaAquarium.org. The Georgia Aquarium. Archived from the original on January 20, 2015. Retrieved January 20, 2015.
  4. ^ a b "Information Bulletin – What is Albinism?". National Organization for Albinism and Hypopigmentation. January 27, 2018. Retrieved June 23, 2020.
  5. ^ McCardle, Hayley (May 2012). Albinism in wild vertebrates (MSc thesis). Texas State University. Retrieved January 24, 2015.
  6. ^ a b c "Oculocutaneous Albinism". NORD (National Organization for Rare Disorders). Retrieved June 23, 2020.
  7. ^ Gunnarsson, Ulrika; Hellström, Anders R.; Tixier-Boichard, Michele; Minvielle, Francis; Bed'hom, Bertrand; Ito, Shin'ichi; Jensen, Per; Rattink, Annemieke; Vereijken, Addie; Andersson, Leif (February 2007). "Mutations in SLC45A2 Cause Plumage Color Variation in Chicken and Japanese Quail". Genetics. 175 (2): 867–877. doi:10.1534/genetics.106.063107. ISSN 0016-6731. PMC 1800597. PMID 17151254.
  8. ^ Brilliant, Murray H. (2001). "The Mouse p (pink-eyed dilution) and Human P Genes, Oculocutaneous Albinism Type 2 (OCA2), and Melanosomal pH". Pigment Cell Research. 14 (2): 86–93. doi:10.1034/j.1600-0749.2001.140203.x. ISSN 1600-0749. PMID 11310796.
  9. ^ a b Kumari, M.; Clarke, H. J.; Small, I.; Siddique, K. H. M. (2009). "Albinism in plants: A major bottleneck in wide hybridization, androgenesis and doubled haploid culture". Critical Reviews in Plant Sciences. 28 (6): 393–409. doi:10.1080/07352680903133252. S2CID 85298264.
  10. ^ a b "Albiflora". Archived from the original on February 2, 2015. Retrieved January 28, 2015.
  11. ^ Mäthger, L. M.; Denton, E. J.; Marshall, N. J.; Hanlon, R. T. (2009). "Mechanisms and behavioural functions of structural coloration in cephalopods". Journal of the Royal Society Interface. 6 (Suppl 2): 149–163. doi:10.1098/rsif.2008.0366.focus. PMC 2706477. PMID 19091688.
  12. ^ Taylor, J. D. (1969). "The effects of intermedin on the ultrastructure of amphibian iridophores". General and Comparative Endocrinology. 12 (3): 405–416. doi:10.1016/0016-6480(69)90157-9. PMID 5769930.
  13. ^ "Albino". MacMillan Dictionary.
  14. ^ "Albino". Cambridge Dictionaries On-line. Retrieved January 31, 2015.
  15. ^ "albino". Dictionary.com Unabridged (Online). n.d. Retrieved August 7, 2019.
  16. ^ "Albinism". Merriam-Webster. Retrieved January 31, 2015.
  17. ^ a b "Leucisam and albinism". BTO.org. British Trust for Ornithology. December 13, 2011. Retrieved January 31, 2015.
  18. ^ a b c de Grouw, H. (2006). "Not every white bird is an albino: Sense and nonsense about colour aberrations in birds" (PDF). Dutch Birding. 28: 79–89. Archived from the original (PDF) on July 13, 2017. Retrieved January 24, 2015.
  19. ^ "Albinism". Encyclopædia Britannica. Retrieved January 27, 2015.
  20. ^ a b c Binkley, S. K. "Color on, color off" (PDF). Retrieved January 22, 2015.
  21. ^ Schalock, Peter C.; Hsu, Jeffrey T. S. (2012). Lippincott's Primary Care Dermatology. Lippincott Williams & Wilkins. p. 641. ISBN 978-1-4511-4877-0. The inheritance pattern for most forms of albinism is autosomal recessive.
  22. ^ Needham, A. E. (2012). The Significance of Zoochromes. Springer. p. 325. ISBN 978-3-642-80766-4. Some dominant chromogenic mutations are known and in fact there are more than predicted by the Haldane-Fisher theory of evolution of wild type dominance (Searle, 1968, p. 250)"..."Of 32 dominant mutations known in the mouse as many as nine are chromogenic (Hadorn, 1961, p. 132). This is a very high percentage of the 40 coal-colour genes known among the mouse and implies that dominant mutations are rather characteristic of colour genes. The dilation gene of the palomino horse is dominant and there is a dominant white in many mammals so that dominance/recessivity is not necessarily positively correlated with excess/deficiency. the dominant white is not so deficient in pigment as the true albino and in particular as the normal eye-pigmentation, so that in Atz' lobster the pigmentation of this organ can be controlled independently of that integument. It would seem that the retention of essential pigment by the dominant white has been naturally selected and that presumably its whole phenotype has been selected. Arctic white races and species no doubt have this type of allele. True recessive albinos lack tyrosinase (Onslow, 1917; Foster, 1952; Barnicott, 1957; Fitzpatrick et al., 1958) or have the enzyme but no free tyrosine (Verne, 1926, p. 535; Fox and Vevers, 1960, p. 37) but in the dominant white the enzyme is present in the skin, under inhibition.
  23. ^ Nakamura, K.; Ozaki (June 2001). "Genetic mapping of the dominant albino locus in rainbow trout (Oncorhynchus mykiss)". Molecular Genetics and Genomics. 265 (4): 687–693. doi:10.1007/s004380100464. PMID 11459189. S2CID 7868741.
  24. ^ Kocher, Thomas D.; Kole, Chittaranjan (2008). Genome Mapping and Genomics in Fishes and Aquatic Animals. Springer Science & Business Media. p. 29. ISBN 978-3-540-73837-4. RSA was also used to identify markers associated with the dominant albino phenotype in a Japanese strain of rainbow trout.
  25. ^ a b c d "Albino animals". Wonders of the Nature. Archived from the original on January 28, 2015. Retrieved January 24, 2015.
  26. ^ a b Nasr, S. R. (July 15, 2008). "How albinism works". HowStuffWorks.com. Retrieved January 23, 2015.
  27. ^ "Albinism in animals". Science Illustrated. 2011. Retrieved January 24, 2015.
  28. ^ Allison, W. T.; Hallows, T. E.; Johnson, T.; Hawryshyn, C.W.; Allen, D. M. (2006). "Photic history modifies susceptibility to retinal damage in albino trout". Visual Neuroscience. 23 (1): 25–34. doi:10.1017/s0952523806231031. PMID 16597348. S2CID 26337580.
  29. ^ a b c Esteve, J. V.; Jeffery, G. (1998). "Reduced retinal deficits in an albino mammal with a cone rich retina: A study of the ganglion cell layer at the area centralis of pigmented and albino grey squirrels". Vision Research. 38 (6): 937–940. doi:10.1016/s0042-6989(97)00229-0. PMID 9624442. S2CID 20900399.
  30. ^ Fausto-Sterling, Anne (2008). Myths Of Gender: Biological Theories About Women And Men (Rev. ed.). Basic Books. p. 172. ISBN 978-0-7867-2390-4. Consider albino animals of the arctic. Hungry predators may have unwittingly selected for the albino color variant by eating more of the easily visible dark-colored variants.
  31. ^ Ilo Hiler, Albinos. Young Naturalist. The Louise Lindsey Merrick Texas Environment Series, No. 6, pp. 28–31. Texas A&M University Press, College Station (1983)
  32. ^ Dobosz, ByS; Kohlmann, K.; Goryczko, K.; Kuzminski, H. (July 2008). "Growth and vitality in yellow forms of rainbow trout". Journal of Applied Ichthyology. 16 (3): 117–120. doi:10.1046/j.1439-0426.2000.00147.x.
  33. ^ Gross, Joshua (June 30, 2016). "A pleiotropic interaction between vision loss and hypermelanism in Astyanax mexicanus cave x surface hybrids". BMC Evolutionary Biology. 16 (1): 145. doi:10.1186/s12862-016-0716-y. ISSN 1471-2148. PMC 4929771. PMID 27363593. S2CID 255789720. Indeed, two Mendelian pigment phenotypes (albinism and brown) are both widespread, highly penetrant, and mediated through loss-of-function mutations in the genes Oca2 and Mc1r, respectively [12, 54]. Recent studies have provided evidence of selection for albinism as a means of increasing catecholamine levels, which promote adaptive feeding and sleep behaviors in Astyanax cavefish.
  34. ^ Pierce, Benjamin A. (2008). Transmission and Population Genetics. Macmillan. p. A1. ISBN 978-1-4292-1118-5. In the Hopi culture, albinos were considered special and given special status. Because extensive exposure to sunlight could be damaging or deadly, Hopi male albinos did no agricultural work. Albinism was considered a positive trait rather than a negative physical condition, allowing albinos to have more children and thus increasing the frequency of the allele.
  35. ^ Shepherd, Rosamond (1996). Founder Effects in Some Victorian Wild Rabbit Oryctolaguscuniculus L. Populations (PDF). Field Naturalists' Club of Victoria. p. 100. There is no apparent reason why selection for albinism should have been greater at Morton Plains thanelse where in north-western Victoria. It is likely that its high occurrence there is a founder effect from the domestic-type feral population established during the 1860s.
  36. ^ Menzel, R. W. (1958). "Further notes on the albino catfish". Journal of Heredity. 49 (6): 284–293. doi:10.1093/oxfordjournals.jhered.a106828.
  37. ^ a b c d Purdom, C. F., ed. (1993). Genetics and Fish Breeding. London: Chapman and Hall. p. 27. ISBN 978-0-412-33040-7. Retrieved February 2, 2015. albinism in fish.
  38. ^ a b c Lechner, W.; Ladich, F. (1987). "How do albino fish hear?". Journal of Zoology. 283 (3): 186–192. doi:10.1111/j.1469-7998.2010.00762.x. PMC 3083522. PMID 21552308.
  39. ^ a b Halls, K. M. (2004). Albino Animals. Minneapolis: Lerner Publishing Group. ISBN 978-1-58196-019-8.
  40. ^ Creel, D. (June 1980). "Inappropriate use of albino animals as models in research". Pharmacology Biochemistry and Behavior. 12 (6): 969–967. doi:10.1016/0091-3057(80)90461-X. PMID 7403210. S2CID 27084719.
  41. ^ "Albinos". Young Naturalist. Texas Parks & Wildlife Department. Retrieved March 21, 2022.
  42. ^ a b Mahabal, Anil; Rane, P. D.; Pati, S. K. (2012). "A case of total albinism in the Bonnet Macaque Macaca radiata (Geoffroy) from Goa" (PDF). Zoos' Print Journal. 27 (12): 22. Archived from the original (PDF) on February 8, 2015. Retrieved January 29, 2015.
  43. ^ Sanil, R.; Shameer, T. T.; Easa, P. S. (2014). "Albinism in jungle cat and jackal along the coastline of the southern Western Ghats". Cat News. 61: 23–25.
  44. ^ Dewsbury, D. A.; Ward, S. E. (1985). "Effects of albinism on copulatory behavior and sperm competition in prairie voles (Microtus ochrogaster)". Bulletin of the Psychonomic Society. 23 (1): 68–70. doi:10.3758/bf03329782.
  45. ^ a b c Fertl, D.; Rosel, P. E. (2008). "Albinism". In Perrin, William F.; Würsig, Bernd; Thewissen, J. G. M. (eds.). Encyclopaedia of Marine Mammals (2nd ed.). Amsterdam: Elsevier. pp. 22–24. ISBN 978-0-12-373553-9.
  46. ^ "Rare Pink Dolphin Seen in Louisiana Lake". Fox News Channel. July 3, 2007. Archived from the original on February 24, 2010. Retrieved February 27, 2010.
  47. ^ "Albino dolphin in northern Gulf of Mexico" (PDF). NOAA. Retrieved January 30, 2015.
  48. ^ "Albino Animals from Snowflake the white gorilla to White Diamond the alligator". The Telegraph
  49. ^ Alaja, P.; Mikkola, H. "Albinism in the Great Gray Owl (Strix nebulosa) and Other Owls" (PDF). Archived from the original (PDF) on August 2, 2018. Retrieved January 24, 2015.
  50. ^ Ren, J. Q.; McCarthy, W. R.; Zhang, H.; Adolphc, A. R.; Lia, L. (2002). "Behavioral visual responses of wild-type and hypopigmented zebrafish". Vision Research. 42 (3): 293–299. doi:10.1016/S0042-6989(01)00284-X. PMID 11809482. S2CID 15140090.
  51. ^ Leal, M. E.; et al. (2013). "First record of partial albinism in two catfish species of Genidens (Siluriformes: Ariidae) in an estuary of Southern Brazil". Brazilian Archives of Biology and Technology. 56 (2): 237–240. doi:10.1590/S1516-89132013000200008.
  52. ^ de Brito, Marcelo F. G.; Caramaschi, Érica P. (2005). "An albino armored catfish Schizolecis guntheri (Siluriformes: Loricariidae) from an Atlantic Forest coastal basin". Neotropical Ichthyology. 3 (1): 123–125. doi:10.1590/S1679-62252005000100009.
  53. ^ Nakaya, K. (1973). "Albino zebra shark from the Indian ocean with comments on albinism in elasmobranchs" (PDF). Japanese Journal of Ichthyology. 20 (2): 120–122. Archived from the original (PDF) on February 2, 2015. Retrieved January 26, 2015.
  54. ^ Bondari, K. (1984). "Comparative performance of albino and normally pigmented channel catfish in tanks, cages, and ponds". Aquaculture. 37 (4): 293–301. doi:10.1016/0044-8486(84)90295-3.
  55. ^ Protas, Meredith E; Hersey, Candace; Kochanek, Dawn; Zhou, Yi; Wilkens, Horst; Jeffery, William R; Zon, Leonard I; Borowsky, Richard; Tabin, Clifford J (2006). "Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism". Nature Genetics. 38 (1): 107–111. doi:10.1038/ng1700. PMID 16341223. S2CID 21421177.
  56. ^ Reum, J. C. P.; Paulsen, C. E.; Pietsch, T. W.; Parker-Stetter, S. L. (2008). "First record of an albino Chimaeriforme fish" (PDF). Northwestern Naturalist. 9: 60–62. doi:10.1898/1051-1733(2008)89[60:FROAAC]2.0.CO;2. S2CID 86529521. Archived from the original (PDF) on March 4, 2016. Retrieved February 2, 2015.
  57. ^ Martin, R. A. "Albinism in sharks". ReefQuest Centre for Shark Research. Retrieved February 2, 2015.
  58. ^ a b Sandoval-Castillo, J.; Mariano-Melendez, E.; Villavicencio-Garayzar, C. (2006). "New records of albinism in two elasmobranchs: The tiger shark Galeocerdo cuvier and the giant electric ray Narcine entemedor". Cybium. 30 (2): 191–192. Retrieved February 2, 2015.
  59. ^ Haith, Sara-Lise (2008). "Rare Albino Whale Shark Spotted". Retrieved November 19, 2020.
  60. ^ Hubbard, G. B.; Fletcher, K. C. (1985). "A seminoma and a leiomyosarcoma in an albino African lungfish (Protopterus dolloi)". Journal of Wildlife Diseases. 21 (1): 72–74. doi:10.7589/0090-3558-21.1.72. PMID 3981753. S2CID 41540530.
  61. ^ The Swamp. California Academy of Sciences
  62. ^ Guthrie, Julian (September 14, 2010) "Albino alligator Claude to mark 15th Birthday". San Francisco Chronicle
  63. ^ "White alligator is one of rarest in world". February 16, 2009. Archived from the original on January 12, 2022. Retrieved September 19, 2018 – via www.telegraph.co.uk.
  64. ^ "Albino crocodile that killed a fisherman shot dead near Darwin – video". The Guardian. August 20, 2014. Retrieved August 11, 2015.
  65. ^ "Albino anole". 2012. Retrieved March 8, 2012.
  66. ^ "Rare albino lizard found in backyard". Australian Broadcasting Corporation. 2007. Retrieved March 8, 2015.
  67. ^ Sage, P. (2006). "Guide to Leopard Gecko Morphs and Genetics". Retrieved March 8, 2015.
  68. ^ a b Modesti, A.; Aguzzi, S.; Manenti, R. (2011). "A case of complete albinism in Lissotriton vulgaris meridionalis" (PDF). Herpetology Notes. 4: 395–396. Archived from the original (PDF) on September 24, 2015. Retrieved January 27, 2015.
  69. ^ Smith-Gill, Sandra J.; Richards, Christina M.; Nace, George W. (May 1972). "Genetic and metabolic bases of two "albino" phenotypes in the leopard frog,Rana pipiens". Journal of Experimental Zoology. 180 (2): 157–167. doi:10.1002/jez.1401800203. hdl:2027.42/38071. ISSN 0022-104X. PMID 4623610.
  70. ^ Miura, Ikuo; Tagami, Masataka; Fujitani, Takeshi; Ogata, Mitsuaki (2017). "Spontaneous tyrosinase mutations identified in albinos of three wild frog species". Genes & Genetic Systems. 92 (4): 189–196. doi:10.1266/ggs.16-00061. PMID 28674275.
  71. ^ Taylor, John William (1900). Monograph of the Land & Freshwater Mollusca of the British Isles. Vol. 1. Taylor Brothers. p. 92.
  72. ^ Taylor, John William (1900). Monograph of the Land & Freshwater Mollusca of the British Isles. Vol. 1. Taylor Brothers. p. 90.
  73. ^ Hoste, B.; Simpson, S. J.; Tanaka, S.; De Loof, A.; Breuer, M. (2002). "A comparison of phase-related shifts in behavior and morphometrics of an albino strain, deficient in [His7]-corazonin, and a normally colored Locusta migratoria strain". Journal of Insect Physiology. 48 (8): 791–801. doi:10.1016/s0022-1910(02)00106-3. PMID 12770057.
  74. ^ Service, Elizabeth. Fruit Fly Phenotypes Archived February 26, 2015, at the Wayback Machine. unc.edu.
  75. ^ a b Zhao, H.; Chen, M.; Yang, H. (2015). "Albinism". In Yang, Hongsheng; Hamel, Jean-Francois; Mercier, Annie (eds.). The Sea Cucumber Apostichopus japonicus: History, Biology and Aquaculture. Academic Press. pp. 211–226. ISBN 978-0-12-799953-1.
  76. ^ Locket, N. A. (1986). "Albinism and eye structure in an Australian scorpion, Urodacus yaschenkoi (Scorpiones, Scorpionidae)". Journal of Arachnology. 14 (1): 101–115. JSTOR 3705557.
  77. ^ Wilkes, J. T. (1963). "A recessive albinism in the citrus red mite". Annals of the Entomological Society of America. 56 (6): 792–795. doi:10.1093/aesa/56.6.792.
  78. ^ Hesford, Clive (January 1998). "The Parblue Puzzle: Part 4 – Common Parblue Varieties: The Cockatiel [Nymphicus hollandicus]" in The Genetics of Colour in the Budgerigar and Other Parrots
  79. ^ Miller, Jessica J. "Amphibian Biology & Physiology: Caudata". LivingUnderworld.com:A Web Project About Amphibians. Archived from the original on May 27, 2007. Retrieved January 18, 2015.
  80. ^ "Feather Colors: What We See" Archived March 28, 2009, at the Wayback Machine by Dr. Julie Feinstein of the American Museum of Natural History (NY), in Birder's World Magazine online archive; sourced December 2006, actual authoring/publication date unspecified.
  81. ^ Stienstra, T. (October 11, 2007). "It's no snow job – handful of redwoods are rare albinos". San Francisco Chronicle. Retrieved December 6, 2010.
  82. ^ a b Krieger, L. M. (November 28, 2010). "Albino redwoods hold scientific mystery". San Jose Mercury News. Retrieved November 23, 2012.
  83. ^ "A Creepy Monster of the Forest: The Albino, Vampiric Redwood Tree". Blogs.DiscoverMagazine.com. December 8, 2010. Archived from the original on September 6, 2019. Retrieved November 23, 2012.
  84. ^ Kerr, E. A. (1963). "Inheritance of crinkle, variegation, and albinism in sweet cherry". Canadian Journal of Botany. 41 (10): 1395–1404. doi:10.1139/b63-122.
  85. ^ "Herbicide Injury". Utah State University. Retrieved November 24, 2021.
  86. ^ "10 Most Incredible Albino Animals on Earth". Scribol. Archived from the original on January 20, 2015. Retrieved January 20, 2015.
  87. ^ "Albino And Leucistic White Animals Are Extremely Rare And Incredibly Beautiful". AnimalsGuide. Retrieved November 18, 2023.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Albinism&oldid=1256283666"