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mitochondrially encoded 12S RNA
Symbol MT-RNR1
Alt. symbols MTRNR1
Entrez 4549
HUGO 7470
Other data
Locus Chr. MT [1]

Mitochondrially encoded 12S RNA (often abbreviated as 12S) is a 959 nt long mitochondrial ribosomal RNA (rRNA). In humans, 12S is encoded by the MTRNR1 gene.

All animal mitochondria genomes contain 37 genes: 2 rRNA, 22 tRNA and 13 mRNA. These are very useful in phylogenetic studies, in particular the 12S and 16S rRNAs.

Mutations in the MTRNR1 gene may be associated with hearing loss.[1]

External links[edit]


  1. ^ Ballana E, Morales E, Rabionet R et al. (March 2006). "Mitochondrial 12S rRNA gene mutations affect RNA secondary structure and lead to variable penetrance in hearing impairment". Biochem. Biophys. Res. Commun. 341 (4): 950–7. doi:10.1016/j.bbrc.2006.01.049. PMID 16458854.