Pepto-Bismol
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Pepto-Bismol
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| Routes | Oral |
Pepto-Bismol is an over-the-counter drug produced by the Procter and Gamble company in the United States of America and in Canada to treat minor digestive system upset. Its active ingredient is bismuth subsalicylate, which is also responsible for its distinctive pink color. The primary symptoms aided by Pepto-Bismol are nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
Pepto-Bismol is made in chewable tablets[1] and swallowable caplets[2], but is best known for its original formula which is a thick liquid. This original formula is a medium pink color with a strong wintergreen flavor. These traits have become generally associated with the medicine to the degree that something may be described as "Pepto-Bismol pink" or as tasting like "Pepto-Bismol".
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[edit] Side effects
Ingesting Pepto-Bismol may cause feces, as well as the tongue, to become dark green or black for several days.[3]
As a contraindication, Pepto-Bismol should never be given to children under twelve or to any child or teen with the flu, chicken-pox, or other viral illness due to the possibility of Reye's Syndrome.[4]
[edit] History
Pepto-Bismol was originally sold as a remedy for infant diarrhea by Norwich Pharmacal Company under the name Bismosal: Mixture Cholera Infantum, changing to Pepto-Bismol in 1919, and transferring to Procter and Gamble with their 1982 acquisition of Norwich Eaton Pharmaceuticals.
[edit] References
- ^ The trademark was extended to cover the tablets in 1973. Registration No. 0972198, November 6, 1973. http://tess2.uspto.gov/bin/showfield?f=doc&state=b8i462.2.2.
- ^ The capsules were introduced in 1983. Registration No. 1269605, March 13, 1984; cancelled July 16, 1990. http://tess2.uspto.gov/bin/showfield?f=doc&state=b8i462.2.1.
- ^ "When a small amount of bismuth combines with trace amounts of sulfur in your saliva and gastrointestinal tract, a black-colored substance (bismuth sulfide) is formed. This discoloration is temporary and harmless." http://www.pepto-bismol.com/faqs.shtml#7
- ^ "This medicine should not be used in children younger than 12 years of age. The fluid loss caused by diarrhea may result in a severe condition. In older children with diarrhea, medicine for diarrhea may be used, but it is also very important that a sufficient amount of liquids be given to replace the fluid lost by the body. If you have any questions about this, check with your health care professional. Also, children are usually more sensitive to the effects of salicylates, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. The bismuth in this medicine may cause severe constipation in children. In addition, do not use this medicine to treat nausea or vomiting in children or teenagers who have or are recovering from the flu or chickenpox. If nausea or vomiting is present, check with the child's doctor immediately because this could be an early sign of Reye's syndrome." http://www.drugs.com/cons/pepto-bismol.html
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