Phenethyl isothiocyanate
Names | |
---|---|
IUPAC name
(2-Isothiocyanatoethyl)benzene
| |
Other names
Phenylethyl isothiocyanate; Phenethyl mustard oil
| |
Identifiers | |
3D model (JSmol)
|
|
Abbreviations | PEITC |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.017.142 |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C9H9NS | |
Molar mass | 163.24 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Phenethyl isothiocyanate (PEITC) is a naturally occurring isothiocyanate that is found in some[which?] cruciferous vegetables.[1]
PEITC has been studied for its potential for chemoprevention of cancers,[2][3] such as prostate cancer.[4]
In terms of biosynthesis, PEITC is produced from gluconasturtiin by the action of the enzyme myrosinase.
References
- ^ "Dictionary of Cancer Terms: PEITC". National Cancer Institute.
- ^ Cheung, KL; Kong, AN (2010). "Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention". The AAPS Journal. 12 (1): 87–97. doi:10.1208/s12248-009-9162-8. PMC 2811646. PMID 20013083.
- ^ Kwon, Ki Han; Xu, Changjiang; Keum, Young-Sam; Khor, Tin Oo; Kim, Jung-Hwan; Huang, Mou-Tuan; Reddy, Bandaru S.; Li, Wenge; Kong, Ah-Ng Tony (2007). "Natural dietary phytochemicals: a promising future for cancer prevention and treatment of earlier lesion". Cancer: Disease Progression and Chemoprevention: 109–126.
- ^ Wang, LG; Chiao, JW (2010). "Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review)". International Journal of Oncology. 37 (3): 533–9. doi:10.3892/ijo_00000702. PMID 20664922.