University constituencies had existed in the United Kingdom Parliament and its predecessors since 1603 and in 1918 Queen's was enfranchised as such. When the Parliament of Northern Ireland was established, the same franchise was preserved - see Queen's University of Belfast (Northern Ireland Parliament constituency).
As with most other Northern Ireland seats in this period, the electorate was heavily inclined towards the Ulster Unionists, with no contests for the Westminster seat taking place at all in the interwar years.
^ abcdefghCraig, F. W. S. (1983) [1969]. British parliamentary election results 1918–1949 (3rd ed.). Chichester: Parliamentary Research Services. p. 675. ISBN0-900178-06-X.