|Locale||Pond Square, Sheffield City Centre|
|Managed by||South Yorkshire Passenger Transport Executive|
|Operators||First South Yorkshire, Stagecoach Sheffield, Stagecoach East Midlands, Stagecoach in Mansfield.|
|Intermodal connection||Yes, Sheffield railway station 200 metres away.|
|Annual usage||Not known|
Sheffield Interchange is the main bus station in central Sheffield, South Yorkshire, England. The facility is served by buses operating across the Sheffield region, as well as National Express coaches which connect Sheffield with many destinations across the United Kingdom. At the northern end of the Interchange is Castle Square tram stop, serving all three Stagecoach Supertram routes. A short distance away via a signposted covered walkway is Sheffield railway station, proving train services to locations across the country.
The majority of services use the Central Bus Station (CBS) site. However, the Interchange also includes two other sites, on Flat Street and Arundel Gate. Both of these are adjacent to and within walking distance of the main CBS site. Directly next to CBS is the Archway Centre, which contains information centres, ticket kiosks, toilets, and a W H Smith store, amongst others.
Formerly called Pond Street bus station, it was opened in 1936. In 1956, covered accommodation was built, replacing the collection of bus stops. From 8 October 1960 it stopped sharing its accommodation with the Sheffield Tramway. In the early 1990s, work began on the reconstruction of the bus station and was renamed Sheffield Interchange. In the early 2000s a large section of the Interchange was demolished due to under use and was subsequently redeveloped. This area is now home to the Digital Campus.
As well as containing around 30 bus stops it also has an information desk, National Express ticket office, public toilets and a WHSmith store within the Archway Centre (the main building). There is also a coach passenger waiting area and a cafe next to the coach stands. The Interchange is integrated with the railway station by way of a signposted covered walkway between the two, it is a short walk from the city centre and the nearest Supertram stop (Fitzalan Square/Ponds Forge).
Sheffield Interchange also has several dedicated coach stands (E1 to E6) which are used by services beginning and terminating at the interchange, as well as several others which are passing through. Stand E1 is the primary pick up/drop off point and this is where the National Express office is located. This should not be confused with the Ticket Office, which is located in the Archway Centre. Sheffield Interchange is also served by a limited number of Stagecoach Express coach routes, as well as other lesser known coach operators. National Express, the primary user, uses the interchange for the following routes: 
- Sheffield, Emerging City, 1969, Sheffield City Council. ISBN 0-901656-01-1
- Great Cities: Sheffield, 2005, Melwyn Jones. ISBN 1-904736-73-4
- "Coach Timetables for Halifax, Huddersfield, Barnsley, Sheffield & London" (PDF). National Express Coaches. National Express. March 2009. Retrieved 2009-08-16.
- "Coach Timetables for Bradford, Leeds and Sheffield to Heathrow & Gatwick" (PDF). National Express Coaches. National Express. March 2009. Retrieved 2009-08-16.
- "National Express Coach Timetables for Sheffield". Travel Search/National Express Coaches. Carl Berry. March 2009. Retrieved 2009-08-16.