Phenylpyruvate decarboxylase
| phenylpyruvate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.1.43 | ||||||||
| CAS no. | 37289-45-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme phenylpyruvate decarboxylase (EC 4.1.1.43) catalyzes the chemical reaction
- phenylpyruvate phenylacetaldehyde + CO2
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming). This enzyme is also called phenylpyruvate carboxy-lyase.[citation needed] This enzyme participates in phenylalanine and tryptophan metabolism.
Structural studies[edit]
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2NXW.
References[edit]
- Asakawa T, Wada H, Yamano T (1968). "Enzymatic conversion of phenylpyruvate to phenylacetate". Biochim. Biophys. Acta. 170 (2): 375–91. doi:10.1016/0304-4165(68)90017-2. PMID 4303395.
