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One of the primary, if not the biggest use of propylene glycol is a safe alternative to ethylene glycol as an antifreeze. That is not mentioned.

This article appears to repeat itself. The second sections contains sentences also present inthe first. I've not got time to do it now (sorry), if someone reads this and it isn't done yet then go for it. I'm just meaning to draw attention to the problem. If it's been fixed then feel free to remove this message. ~Mullet

The cemical formular does not match the pitcher (Written by User:62.252.64.15)

It does as far as I can see. Cacycle 21:32, 16 Jun 2005 (UTC)

The chemical formula matches the picture, but the picture does not match the actual structure. One of the hydroxy groups should be attached to the central carbon atom, instead of a terminal one: CH3-CHOH-CH2OH -- Cvitols 6 July 2005 20:26 (UTC)

Oops. I have corrected the image. Cacycle 6 July 2005 22:49 (UTC)

Merged

Merged from dup article Propylenglycol. Vsmith 14:21, 6 December 2005 (UTC)[reply]

== needs infobox ==liuhlihlkhlkhlkhklhkljh

This substance needs a standard chemical infobox, like other chemical compunds... for example Ethylene glycol. Jamie 01:38, 10 December 2005 (UTC)[reply]

antibacterial?

the deodorant page links to here claiming that propylene glycol is an antibacterial. is this so? source info is pretty weak, http://www.chemicalland21.com/petrochemical/PROPYLENE%20GLYCOL.htm Dreamer.redeemer 07:02, 21 January 2006 (UTC)[reply]

metabolic process?

The article states that PG metabolizes into lactic acid. 1) citation is needed. 2) aside from the h20 + lactic acid breakdown, other compounds are possible... i'm no chemist, but someone smarter than myself should be able to square this puppy up. —Preceding unsigned comment added by 75.70.87.124 (talk) 00:08, 3 January 2008 (UTC)[reply]

use as a laxitive?

A friend of mine said his mother was prescribed PG for relief of constipation at a hospital and that it worked very well. I haven't researched the net yet for this - any comments?

IUPAC name

This article says the IUPAC name is 1,2-propanediol. Should it be propane-1,2-diol instead? --Der yck C. 09:22, 24 October 2006 (UTC)[reply]

Use in Paintballs

Polyethylene Glycol is the main ingredient in paintballs, not Propylene Glycol. http://www.severepaintball.com/pdf/msds.pdf (link to a pdf for the MSDS for a certain brand of paintballs) http://paintball.about.com/b/a/079179.htm (about.com article that mentions polyethylene glycol as the main ingredient)

The tasteless flavoring agent?

I want to know how it's used "as a flavoring agent in Angostura and Orange bitters" when the description also says it's "tasteless". Something doesn't match up there. -- JdwNYC 21:33, 16 December 2006 (UTC)[reply]

You're right. Using it as a flavoring agent doesn't make any sense. I did some reading, PG is used as an emulsifying agent in flavors and citrus concentrations. Because the citrus flavor is an oil, it won't mix evenly with water based solutions unless an emulsifier is added. Nice catch. Oasisbob 23:32, 16 December 2006 (UTC)[reply]

ps. This will be a fun one to google in a few months and see how many sources still cite PG "as a flavoring agent in Angostura and Orange Bitters". Oasisbob 23:34, 16 December 2006 (UTC)[reply]

FDA Safe or Not???

Safe or not? The FDA contradicts itself?

According to this article, the FDA has ruled propylene glycol in cat food to be "in violation of the Federal Food, Drug, and Cosmetic Act. 21CFR589.1001"

The next paragraph says the FDA has ruled "propylene glycol to be "generally recognized as safe" for use in food, cosmetics, and medicines."

So, which is it?? Did the FDA rule it safe for food or not? Or is it perfectly safe for all mammals to eat EXCEPT cats? This article raises more questions than it answers for the great amount of people that look this up to answer the question: should I or my pets be eating this or not?

I'm sure the FDA did not simultaneously rule it to be safe and not safe. We need to figure out which it is and get rid of the other one. If it somehow is both, we need to explain how and why.

Andrew

24.91.195.62 17:30, 23 June 2007 (UTC)[reply]

Generally Recognized As Safe (GRAS) is a term used by the FDA to indicate a substance is thought to be safe for human beings, not every species on the planet. Cats are not teeny-tiny people. They're obligate carnivores, not omnivores. Propylene glycol will create Heinz bodies (a type of red blood cell) in felines, resulting in oxidative damage. DO NOT give propylene glycol to cats.

According to the USDA (FSIS Directive 7120.1 Ammendment 8) Lauramide arginine dissolved in propylene glycol can be added to fresh meat and poultry, and may be listed on the label as just plain lauric arginate. Also, in solutions intended as antimicrobials, it can be added to fresh meat and poultry WITHOUT mentioning it on the label. You can't tell by the label what's on the food, so be careful feeding your cat human food, even boiled chicken.

Honestly, what they're doing to the food is scary.

I agree. What is propylene glycol doing in muffins made by Vons (major Westcoast supermarket chain)? Why is a non-food ingredient allowed in food? [User: Sandiegan6423, 12 February 2008 —Preceding unsigned comment added by Sandiegan6423 (talk • contribs) 19:12, 12 February 2008 (UTC)[reply]

Yes, its a worry. I recently bought a Boston Cream Pie from Vons, and the propylene glycol was listed higher on the ingredients list than the shortening! I guess that goes for 'whipped topping' too. My main question/concern with propylene glycol in our diet is this: Once it gets into our digestive tracts, and breaks down to create higher acidity levels, how does that then interact with the phthalates and other plastics that we are inevitably taking into our bodies by using plastic food containers every day. Do the phthalates become more bioavailable and more genotoxic? We won't know until someone tests this out, and it's not an easy one to test. Clarafury (talk) 05:41, 17 February 2008 (UTC)[reply]

FAA questioning environmental impact

A chemical used by Alaska aviators to prevent their aircraft from icing up in the winter is getting new scrutiny from environmental regulators. The state plans to adopt a rule that would classify the anti-icing fluid, sprayed on planes before they take off, as a contaminant that could require an industrial cleanup.

| Anchorage Daily News article

However, while ethylene glycol and propylene glycol are both biodegradable, propylene glycol degrades at a slower rate and has a greater biochemical oxygen demand. Thus, propylene glycol will remain in the environment longer than ethylene glycol and will consume more oxygen while it is being broken down. Therefore, it can still be harmful to the environment.

| Bioremediation of Aircraft Deicing Fluids (Glycol) at Airports. (PDF)

I wasn't sure how to include this reference in the article, so someone please feel free to do such. --Xitit 18:31, 21 October 2007 (UTC)[reply]

Redundant

a "Colorless, Clear liquid is redundant." —Preceding unsigned comment added by 97.86.161.46 (talk) 17:51, 8 February 2008 (UTC)[reply]

No it's not, there can be clear red liquids or colorless opaque liquids.Mr Bungle | talk 20:38, 8 February 2008 (UTC)[reply]

Tasteless and slightly sweet?

I guess one of them must be wrong. —Preceding unsigned comment added by 213.39.149.219 (talk) 01:17, 2 May 2008 (UTC)[reply]

Psychosis in recent cases

How has no one edited this page for psychosis? We are having people in the ER experience psychosis with new IV injections that contain propylene glycol as a co-solvent for water-immiscible drugs, such as phenytoin. Can someone please find the sources from journals on the emerging cases? I'm not saying this is an emergency, but wikipedia should have this information by now... —Preceding unsigned comment added by 128.62.142.166 (talk) 20:12, 11 May 2008 (UTC)[reply]

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VERY SCARY cross check the ingredients on various personal items with the National Toxicology Program...

Bold textPropylene oxide is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals (NTP 1984, IARC 1985, 1987, 1994). When administered by inhalation, propylene oxide induced hemangiomas or hemangiosarcomas of the nasal cavity in mice of both sexes. When administered by inhalation, propylene oxide increased the incidences of papillary adenomas of the nasal turbinates in rats of both sexes (NTP 1984).

Propylene oxide is used primarily as a chemical intermediate in the production of polyurethane polyols (60% to 65%), propylene glycols (20% to 25%), glycol ethers (3% to 5%), and specialty chemicals. Polyurethane polyols are used to make polyurethane foams; whereas, propylene glycols are primarily used to make unsaturated polyester resins for the textile and construction industries. Propylene glycols are also used in drugs, cosmetics, solvents and emollients in food, plasticizers, heat transfer and hydraulic fluids, and antifreezes. In addition, propylene oxide may be used in fumigation chambers for the sterilization of packaged foods and as a pesticide (IARC 1994, HSDB 2001). —Preceding unsigned comment added by Kaybaby (talk • contribs) 01:52, 16 August 2008 (UTC)[reply]

Cops found it in my spirit

The documents write that because spirit contained propylene glycol, the spirit must have been made from industrial ethanol. What propylene glycol has to do with ethanol? It seems it is non-toxic, but does it go with some particular denaturing substance, or is just naturally produced during industrial ethanol production, just like small-amounts of methanol are produced during fermentation? Documents do not mention anything else. Any460 (talk) 15:12, 2 March 2009 (UTC)[reply]

@@ Line 124: / Line 124: @@
 oxide may be used in fumigation chambers for the sterilization of
 packaged foods and as a pesticide (IARC 1994, HSDB 2001).  <small>—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:Kaybaby|Kaybaby]] ([[User talk:Kaybaby|talk]] • [[Special:Contributions/Kaybaby|contribs]]) 01:52, 16 August 2008 (UTC)</small><!-- Template:Unsigned --> <!--Autosigned by SineBot-->
+==Cops found it in my spirit==
+The documents write that because spirit contained propylene glycol, the spirit must have been made from industrial ethanol. What propylene glycol has to do with ethanol? It seems it is non-toxic, but does it go with some particular denaturing substance, or is just naturally produced during industrial ethanol production, just like small-amounts of methanol are produced during fermentation? Documents do not mention anything else. [[User:Any460|Any460]] ([[User talk:Any460|talk]]) 15:12, 2 March 2009 (UTC)