RO5256390
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Chemical and physical data | |
Formula | C13H18N2O |
Molar mass | 218.300 g·mol−1 |
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RO-5256390 is a drug developed by Hoffmann-La Roche which acts as an agonist for the trace amine associated receptor 1, which has been shown to block compulsive and binge-like eating behavior in rats. For this reason, it is being investigated as a potential drug to treat binge eating disorder.[1][2]
Reference section
- ^ Ferragud, Antonio; Howell, Adam D.; Moore, Catherine F.; Ta, Tina L.; Hoener, Marius C.; Sabino, Valentina; Cottone, Pietro (June 2017). "The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats". Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology. 42 (7): 1458–1470. doi:10.1038/npp.2016.233. ISSN 1740-634X. PMC 5436108. PMID 27711047.
- ^ "RO5256390". MedChem Express. Retrieved 11 August 2023.
Category:TAAR1 agonists Category:Oxazolines