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Trace amine associated receptor 2
Symbols TAAR2 ; GPR58; taR-2
External IDs OMIM604849 MGI2685071 HomoloGene110760 IUPHAR: 167 GeneCards: TAAR2 Gene
RNA expression pattern
PBB GE TAAR2 221394 at tn.png
More reference expression data
Species Human Mouse
Entrez 9287 209512
Ensembl ENSG00000146378 ENSMUSG00000059763
UniProt Q9P1P5 Q5QD17
RefSeq (mRNA) NM_001033080 NM_001007266
RefSeq (protein) NP_001028252 NP_001007267
Location (UCSC) Chr 6:
132.62 – 132.62 Mb
Chr 10:
23.94 – 23.94 Mb
PubMed search [1] [2]

Trace amine-associated receptor 2 is a protein that in humans is encoded by the TAAR2 gene.[1][2][3]

A recent paper showed that, along with TAAR1, TAAR2 is required for full activity of trace amines in PMN cells.[4]

See also[edit]


  1. ^ Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, Liu Y, Liu IS, Heng HH, Seeman P, George SR, O'Dowd BF, Marchese A (Jun 2000). "Cloning and characterization of additional members of the G protein-coupled receptor family". Biochim Biophys Acta 1490 (3): 311–23. doi:10.1016/s0167-4781(99)00241-9. PMID 10684976. 
  2. ^ Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (Feb 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104. 
  3. ^ "Entrez Gene: TAAR2 trace amine associated receptor 2". 
  4. ^ Babusyte A, Kotthoff M, Fiedler J, Krautwurst D (March 2013). "Biogenic amines activate blood leukocytes via trace amine-associated receptors TAAR1 and TAAR2". J. Leukoc. Biol. 93 (3): 387–94. doi:10.1189/jlb.0912433. PMID 23315425. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.