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Allan Balmain

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Allan Balmain
Allan Balmain at the Royal Society admissions day in London, July 2015
Alma materUniversity of Glasgow (BSc, PhD)
Awards
Scientific career
Fields
Institutions
ThesisStudies in the diterpenoid field (1969)
Website

Allan Balmain FRS[1] FRSE is Barbara Bass Bakar Distinguished Professor of Cancer Genetics[2] at the University of California, San Francisco (UCSF).[7][8][9][10][11]

Education

Balmain was educated at the University of Glasgow where he was awarded a Bachelor of Science degree in chemistry in 1966, followed by a PhD on the organic chemistry of terpenoids in 1969.[2]

Awards and honours

Balmain was elected a Fellow of the Royal Society (FRS) in 2015. His certificate of election reads:

Allan Balmain has pioneered the use of the mouse as a model system for understanding the complexity of cancer at a genetic, molecular and cellular level. Through his novel and creative experiments he established the first molecular link between cancer initiation and carcinogen exposure, identified how specific genetic events lead to malignant progression and made major advances in our understanding of cancer susceptibility. Balmain's wide-ranging, innovative use of mouse genetics has generated new approaches for visualizing the genetic architecture of cancer pathways and the roles of complex network interactions in determining an individual's cancer susceptibility.[1]

Balmain was also elected a Fellow of the Royal Society of Edinburgh (FRSE) in 1995.[2]

References

  1. ^ a b c "Professor Allan Balmain FRS". London: The Royal Society. Archived from the original on 2 May 2015.
  2. ^ a b c d e "Allan Balmain, PhD, FRSE". University of California, San Francisco. Archived from the original on 6 February 2013.
  3. ^ Balmain, A; Gray, J; Ponder, B (2003). "The genetics and genomics of cancer". Nature Genetics. 33 Suppl (3s): 238–44. doi:10.1038/ng1107. PMID 12610533. S2CID 8379885.
  4. ^ Quigley, D. A.; To, M. D.; Kim, I. J.; Lin, K. K.; Albertson, D. G.; Sjolund, J.; Pérez-Losada, J. S.; Balmain, A. (2011). "Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility" (PDF). Genome Biology. 12: R5. doi:10.1186/gb-2011-12-1-r5. PMC 3091303. PMID 21244661. Open access icon
  5. ^ Cui, W.; Fowlis, D. J.; Bryson, S.; Duffie, E.; Ireland, H.; Balmain, A.; Akhurst, R. J. (1996). "TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice". Cell. 86 (4): 531–542. doi:10.1016/S0092-8674(00)80127-0. PMID 8752208. S2CID 18065761.
  6. ^ Merritt, A. J.; Potten, C. S.; Kemp, C. J.; Hickman, J. A.; Balmain, A; Lane, D. P.; Hall, P. A. (1994). "The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice". Cancer Research. 54 (3): 614–7. PMID 8306319.
  7. ^ Derynck, R; Akhurst, R. J.; Balmain, A (2001). "TGF-beta signaling in tumor suppression and cancer progression". Nature Genetics. 29 (2): 117–29. doi:10.1038/ng1001-117. PMID 11586292. S2CID 9923320.
  8. ^ Quintanilla, M; Brown, K; Ramsden, M; Balmain, A (1986). "Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis". Nature. 322 (6074): 78–80. Bibcode:1986Natur.322...78Q. doi:10.1038/322078a0. PMID 3014349. S2CID 4353576.
  9. ^ Allan Balmain's publications indexed by the Scopus bibliographic database. (subscription required)
  10. ^ Balmain, A.; Barrett, J. C.; Moses, H.; Renan, M. J. (1993). "How many mutations are required for tumorigenesis? Implications from human cancer data". Molecular Carcinogenesis. 7 (3): 139–146. doi:10.1002/mc.2940070303. PMID 8489711. S2CID 29456469.
  11. ^ Balmain, A.; Ramsden, M.; Bowden, G. T.; Smith, J. (1984). "Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas". Nature. 307 (5952): 658–660. Bibcode:1984Natur.307..658B. doi:10.1038/307658a0. PMID 6694757. S2CID 4254723.


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