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This is an old revision of this page, as edited by NikoSilver (talk | contribs) at 13:56, 15 October 2020 (→‎Estimated Release Date: new section). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

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RfC: emergency approval authorization

The UAE has approved Sinopharm's Covid-19 vaccine for frontline workers following successful Phase III clinical trials in Abu Dhabi. "The results of studies during the final stages of the Phase III trial showed that the vaccine is effective and resulted in a strong response, and the generation of antibodies to the virus. Studies on the safety of the vaccination have been reviewed and showed that it is safe and safe for use." said Minister of Health Abdulrahman Al Owais. The WHO-recognized trial began on July 16 and involved 31,000 volunteers. (The National).

This is significant in that a 3rd party government has approved of emergency use of COVID-19 vaccine following two months of Phase III trials. Its quite different from China and Russia's earlier approval of vaccine use which generated some skepticism since emergency approval was prior to Phase III testing and also the vaccine was developed by the respective countries, hence fears of "vaccine nationalism." I have included a small blurb in the vaccine table showing emergency approval in the UAE for healthcare workers. Am interested in hearing other proposals, as emergency approvals from other countries will also start coming hard and fast. Albertaont (talk) 20:59, 14 September 2020 (UTC)[reply]

  • Oppose. This is news and, imo, transient, unencyclopedic information - WP:NOTNEWS. There's no possibility of a "successful" Phase III trial result obtained in 2 months (months-years for a typical vaccine). "Interim" results are not final, but rather a glimpse of a trend in data, and the safety conclusion by the UAE minister is premature. In this case, the only safety data published are from the Phase I-II trials on less than 100 people per group - PMID 32789505. Governments are free to declare EUA for their own situation - which will generate news - but an encyclopedia should rely on evidence from published results to justify a decision to approve EUA or not. Zefr (talk) 23:09, 14 September 2020 (UTC)[reply]

New review

Should be useful:

  • Tregoning JS, Brown ES, Cheeseman HM, Flight KE, Higham SL, Lemm NM, Pierce BF, Stirling DC, Wang Z, Pollock KM (2020). "Vaccines for COVID‐19". Clinical & Experimental Immunology (Review). doi:10.1111/cei.13517. ISSN 0009-9104.

Alexbrn (talk) 07:41, 18 September 2020 (UTC)[reply]

Janssen phase III

The Janssen candidate (Ad26.COV2.S) has begun its 60,000-strong phase III trial. Should this be updated in the table?

https://www.jnj.com/johnson-johnson-initiates-pivotal-global-phase-3-clinical-trial-of-janssens-covid-19-vaccine-candidate

I Am RufusConversation is a beautiful thing. 11:26, 23 September 2020 (UTC)[reply]

Estimated Release Date

I think the single most important question any reader has when seeking articles of the sort is "WHEN"!

- The table under COVID-19 vaccine#Vaccine candidates cannot be sorted accordingly. The last column of 'Duration' should split in two so that one can sort using end-dates for the phases, and dates should be written in the format yyyy-mm(-dd) so that this is feasible.

- Also certain vaccines have been approved for "Early or Limited Use" in certain countries (e.g. to medical staff, soldiers etc). This link by the New York Times has a great graphic with the number of vaccines in every phase right at the top and a whole section with details on this. There should be a greener color for those vaccines in the table and these details should be included (if the informed editors here think this or other sources of the sort are reliable).

- And finally there are some other early releases due to political (not necessarily 100% scientific) decisions which should be mentioned. A large number of politicians obviously think the economic consequences and/or the disease itself can lead to graver health problems than the possible side effects.

All of the above can help the reader understand better the possible answer to the "WHEN" question at a glance. NikoSilver 13:56, 15 October 2020 (UTC)[reply]