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(+)-Pulegone reductase

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(+)-pulegone reductase
Identifiers
EC no.1.3.1.81
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

(+)-pulegone reductase (EC 1.3.1.81) is an enzyme with systematic name (−)-menthone:NADP+ oxidoreductase.[1] This enzyme catalises the following chemical reaction

(1) (−)-menthone + NADP+ (+)-pulegone + NADPH + H+
(2) (+)-isomenthone + NADP+ (+)-pulegone + NADPH + H+

NADH cannot replace NADPH as reductant.

References

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  1. ^ Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R (October 2003). "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics. 418 (1): 80–92. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086.
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