2,5-dioxopiperazine hydrolase

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2,5-dioxopiperazine hydrolase
Identifiers
EC number 3.5.2.13
CAS number 97599-45-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a 2,5-dioxopiperazine hydrolase (EC 3.5.2.13) is an enzyme that catalyzes the chemical reaction

2,5-dioxopiperazine + H2O glycylglycine

Thus, the two substrates of this enzyme are 2,5-dioxopiperazine and H2O, whereas its product is glycylglycine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 2,5-dioxopiperazine amidohydrolase. Other names in common use include cyclo(Gly-Gly) hydrolase, and cyclo(glycylglycine) hydrolase.

References[edit]

  • Suzuki Y; Uchida K (1985). "Multiple forms of alpha-glycosidase from pig duodenum". Agric. Biol. Chem. 49: 1573–1581. doi:10.1271/bbb1961.49.1573.