The 2000 National Lacrosse League season is the 14th season in the NLL that began on January 7, 2000, and concluded with the championship game on May 6, 2000. The Toronto Rock defeated the Rochester Knighthawks 14–13. Kaleb Toth scored the winning goal with less than two seconds left in regulation to give the Rock their second straight championship.
x: Clinched playoff berth; c: Clinched playoff berth by crossing over to another division; y: Clinched division; z: Clinched best regular season record; GP: Games Played W: Wins; L: Losses; GB: Games back; PCT: Win percentage; Home: Record at Home; Road: Record on the Road; GF: Goals scored; GA: Goals allowed Differential: Difference between goals scored and allowed; GF/GP: Average number of goals scored per game; GA/GP: Average number of goals allowed per game