Intracameral injection
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| Intracameral injection | |
|---|---|
 Intravitreal administration delivers substances directly into the anterior chamber of eyeball. | |
| Specialty | ophthalmology |
An intracameral injection is an injection of a substance (usually an antibiotic) into the eye cavities (i.e. camerae) for the prevention of endophthalmitis or infection of the eye that can occur after cataract surgery. The Food and Drug Administration (FDA) has not approved antibiotics for this use and it is considered 'off-label'. Concerns about this procedure contributing to increasing numbers of antibiotic resistant organisms have been expressed.[1]
In the UK, Aprokam cefuroxime has been approved for use in intracameral injections.[2] Intracameral injection of recombinant tissue plasminogen activator (r-TPA) has been found to be effective in treating the development of fibrin intraocularly after the development of endophthalmitis.[3]
References
- ^ Editor, Christopher Kent, Senior. "Antibiotics & Cataract Surgery: New Frontiers". Retrieved 3 April 2017.
{{cite web}}:|last=has generic name (help)CS1 maint: multiple names: authors list (link) - ^ "Aprokam cefuroxime 50mg powder for solution for injection - Summary of Product Characteristics (SPC) - (eMC)". Retrieved 3 April 2017.
- ^ Wu, T-T; Wang, H-H (2007). "Intracameral recombinant tissue plasminogen activator for the treatment of severe fibrin reaction in endophthalmitis". Eye. 23 (1): 101–107. doi:10.1038/sj.eye.6702984. ISSN 0950-222X.
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