Acyl-lysine deacylase
Appearance
acyl-lysine deacylase | |||||||||
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Identifiers | |||||||||
EC no. | 3.5.1.17 | ||||||||
CAS no. | 9025-11-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an acyl-lysine deacylase (EC 3.5.1.17) is an enzyme that catalyzes the chemical reaction
- N6-acyl-L-lysine + H2O a carboxylate + L-lysine
Thus, the two substrates of this enzyme are N6-acyl-L-lysine and H2O, whereas its two products are carboxylate and L-lysine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N6-acyl-L-lysine amidohydrolase. Other names in common use include epsilon-lysine acylase, and 6-N-acyl-L-lysine amidohydrolase. This enzyme participates in lysine degradation.
References
- PAIK WK, BLOCH-FRANKENTHAL L, BIRNBAUM SM, WINITZ M, GREENSTEIN JP (1957). "epsilon-lysine acylase". Arch. Biochem. Biophys. 69: 56–66. doi:10.1016/0003-9861(57)90472-1. PMID 13445179.