Aspartate N-acetyltransferase
| aspartate N-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.17 | ||||||||
| CAS no. | 9029-99-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an aspartate N-acetyltransferase (EC 2.3.1.17) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + L-aspartate CoA + N-acetyl-L-aspartate
Thus, the two substrates of this enzyme are acetyl-CoA and L-aspartate, whereas its two products are CoA and N-acetyl-L-aspartate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-aspartate N-acetyltransferase. Other names in common use include aspartate acetyltransferase, and L-aspartate N-acetyltransferase.
References
- Goldstein FB (1959). "Biosynthesis of N-acetyl-L-aspartic acid". J. Biol. Chem. 234: 2702–2706.
- Knizley H (October 1967). "The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder". The Journal of Biological Chemistry. 242 (20): 4619–22. PMID 6061408.
