Jump to content

Pritelivir

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Fswitzer4 (talk | contribs) at 14:09, 26 May 2020 (Validated CAS and added FDA UNII). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Pritelivir
Names
IUPAC name
N-Methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-(4-pyridin-2-yl-phenyl)acetamide
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C18H18N4O3S2/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15/h3-10H,11H2,1-2H3,(H2,19,24,25)
    Key: IVZKZONQVYTCKC-UHFFFAOYSA-N
  • InChI=1/C18H18N4O3S2/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15/h3-10H,11H2,1-2H3,(H2,19,24,25)
    Key: IVZKZONQVYTCKC-UHFFFAOYAL
  • Cc1c(sc(n1)N(C)C(=O)Cc2ccc(cc2)c3ccccn3)S(=O)(=O)N
Properties
C18H18N4O3S2
Molar mass 402.49 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Pritelivir (BAY 57-1293) is an antiviral helicase-primase complex inhibitor.[1]

References

  1. ^ Wozniak, M. A; Frost, A. L; Itzhaki, R. F (2013). "The helicase-primase inhibitor BAY 57-1293 reduces the Alzheimer's disease-related molecules induced by herpes simplex virus type 1". Antiviral Research. 99 (3): 401–4. doi:10.1016/j.antiviral.2013.07.003. PMID 23867133.