Aminoimidazolase

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
aminoimidazolase
Identifiers
EC number3.5.4.8
CAS number9025-17-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an aminoimidazolase (EC 3.5.4.8) is an enzyme that catalyzes the chemical reaction

4-aminoimidazole + H2O unidentified product + NH3

Thus, the two substrates of this enzyme are 4-aminoimidazole and H2O, whereas its two products are unidentified product and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 4-aminoimidazole aminohydrolase. This enzyme is also called 4-aminoimidazole hydrolase. This enzyme participates in purine metabolism. It employs one cofactor, iron.

References[edit]

  • Pricer WE, Rabinowitz JC (October 1956). "Purine fermentation by Clostridium cylindrosporum. V. Formiminoglycine" (PDF). The Journal of Biological Chemistry. 222 (2): 537–54. PMID 13367024.