NAGA (gene)

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NAGA
Protein NAGA PDB 3H53.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNAGA, D22S674, GALB, alpha-N-acetylgalactosaminidase
External IDsMGI: 1261422 HomoloGene: 221 GeneCards: NAGA
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for NAGA
Genomic location for NAGA
Band22q13.2Start42,058,354 bp[1]
End42,070,842 bp[1]
RNA expression pattern
PBB GE NAGA 202944 at fs.png

PBB GE NAGA 202943 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000262
NM_001362848
NM_001362850

NM_008669
NM_001355546

RefSeq (protein)

NP_000253
NP_001349777
NP_001349779
NP_000253.1

NP_032695
NP_001342475

Location (UCSC)Chr 22: 42.06 – 42.07 MbChr 15: 82.33 – 82.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha-N-acetylgalactosaminidase is an enzyme that in humans is encoded by the NAGA gene.[5]

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).[5]

References[edit]

Further reading[edit]