Big Darby Creek
|Big Darby Creek|
|River mouth||Scioto River, Columbus, Ohio|
|River system||Lower Scioto River Basin|
|Basin size||556.6 square miles (1,442 km2)|
|Length||84 miles (135 km)|
The river runs 84 miles (135 km) from its source near the Champaign-Union county line, south-east through Union and Madison Counties. In Franklin County, the river runs through the 6856-acre Battelle Darby Creek Metro Park, where it meets with the Little Darby Creek. Directly downstream from the park, the river empties into the Scioto River in Pickaway County at .
The Big Darby Creek is one of the most biologically diverse aquatic systems in the Midwest. It is the site of the only known population of the Scioto madtom, a fish which is now thought to be extinct. In addition, for its size the creek "has the greatest diversity of freshwater mussels in North America. Forty species have been reported from the system." 
When The Columbus Dispatch published an article in 1967 revealing the City of Columbus' plans to purchase over four thousand acres (16 km²) along the creek to build a reservoir, a political and legal battle ensued between the municipality and several environmental groups working with the Ohio Department of Natural Resources. From 1974 to 1984, both sides exchanged victories and the legal battle continued into the Ohio Supreme Court, who ended the battle by ruling that 'scenic river designation' was constitutional. On June 22, 1984, the Upper and Lower Darby Creeks were designated a state scenic river, and then a national scenic river on October 3, 1994.
In 2008, the Columbus Zoo and Aquarium announced plans to build a new exhibit focusing on the Big Darby Creek, and its more than 38 rare species of fish and mussels, and in December, 2009, the City of Columbus, Franklin County Metro Parks, the Ohio Nature Conservancy and other companies announced that they will be spending more than $6 million on seven projects designed to restore sections of Big Darby Creek and its tributaries.
- Franklin County Metro Parks, Battelle Darby Creek Metro Park
- The Nature Conservancy, Darby Creek Watershed
- USFWS. Noturus trautmani Five-year Review. December 2009.
- Ohio Department of Natural Resources, Big Darby Creek State and National Scenic River.
- Narciso, D. Zoo exhibit to spotlight Big Darby Creek. The Columbus Dispatch January 13, 2008.
- Hunt, S. and T. Baker. Crooked creeks. The Columbus Dispatch December 13, 2009.