Boluspor became a professional club when they entered the TFF Second League during the 1966–67 season. They were first promoted into the TFF First League after the 1969–70 season. They were promoted to the Süper Lig in 1972–73 and finished third, their highest finish in the Süper Lig, the following season.
The club has competed in continental competition once, losing to Dinamo Bucharest, in the 1974–75 UEFA Cup. They also competed in the now defunct Balkans Cup, winning matches against clubs such as Sofya Akademik and Sport Clup Bacau, but never won the cup.