Olfactory glands

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Olfactory glands
Section of the olfactory mucous membrane.
Latin glandulae olfactoriae
Code TH H3.
TA A15.1.00.003
TH H3.
FMA 77659
Anatomical terminology

Olfactory glands, also known as Bowman's glands are situated in the olfactory mucosa, beneath the olfactory epithelium, in the lamina propria, a connective tissue also containing fibroblasts, blood vessels, and bundles of fine axons from the olfactory neurons.[1]

An olfactory gland consists of an acinus in the lamina propria and a secretory duct going out through the olfactory epithelium.

Electron microscopy studies show that olfactory glands contain cells with large secretory vesicles.[2] Olfactory glands secrete the gel-forming mucin MUC5AC(UniProtKB: P98088).[3] Olfactory glands might secrete proteins such as lysozyme, amylase and IgA similarly to serous glands. The exact composition of the secretions from olfactory glands is unclear, but there is evidence that they produce odorant binding protein.[4][5]

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This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

  1. ^ Moran, David T.; Rowley Jc, 3rd; Jafek, BW; Lovell, MA (1982), "The fine structure of the olfactory mucosa in man", Journal of Neurocytology, 11 (5): 721–746, doi:10.1007/BF01153516, PMID 7143026 
  2. ^ Frisch, Donald (1967), "Ultrastructure of mouse olfactory mucosa.", The American Journal of Anatomy, 121 (1): 87–120., doi:10.1002/aja.1001210107, PMID 6052394 
  3. ^ Solbu, T. T.; Holen, T. (2012), "Aquaporin pathways and mucin secretion of olfactory glands might protect the olfactory mucosa.", Chemical Senses, 37 (1): 35–46., doi:10.1093/chemse/bjr063, PMID 21745799 
  4. ^ Gartner, Lesli. Color Textbook of Histology. Saunders Elsevier. p. 349. 
  5. ^ Tegoni, Mariella; Pelosi, P; Vincent, F; Spinelli, S; Campanacci, V; Grolli, S; Ramoni, R; Cambillau, C (2000), "Mammalian odorant binding proteins", Biochimica et Biophysica Acta (published 1967), 1482 (1–2): 229–240., doi:10.1016/S0167-4838(00)00167-9, PMID 11058764 

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