COG4

COG4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3HR0
Identifiers
Aliases	COG4, CDG2J, COD1, component of oligomeric golgi complex 4, SWILS
External IDs	OMIM: 606976; MGI: 2142808; HomoloGene: 7155; GeneCards: COG4; OMA:COG4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	70,523,560 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	111,608,859 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; apex of heart; ; muscle of thigh; ; right testis; ; granulocyte; ; gastrocnemius muscle; ; rectum; ; left testis; ; ventricular zone; ; right adrenal gland;
	Top expressed in
	interventricular septum; ; spermatocyte; ; spermatid; ; internal carotid artery; ; muscle of thigh; ; external carotid artery; ; facial motor nucleus; ; skeletal muscle tissue; ; right kidney; ; proximal tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding;
Cellular component	Golgi transport complex; Golgi membrane; Golgi apparatus; membrane; trans-Golgi network membrane; cytoplasm; cytosol;
Biological process	protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport; retrograde transport, vesicle recycling within Golgi; Golgi vesicle prefusion complex stabilization; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; Golgi organization;
	Sources:Amigo / QuickGO
Orthologs
	25839
	102339
	ENSG00000103051
	ENSMUSG00000031753
	Q9H9E3
	Q8R1U1
	NM_001195139; NM_015386; NM_001365426; NM_145818
	NM_133973; NM_001310607
	NP_001182068; NP_056201; NP_001352355
	NP_001297536; NP_598734
	Wikidata
View/Edit Human	View/Edit Mouse

Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.^[5]^[6]

Template:PBB Summary

Interactions

COG4 has been shown to interact with COG7,^[7] COG2,^[7] COG1^[7] and COG5.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000103051 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031753 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function". J Cell Biol. 157 (3): 405–15. doi:10.1083/jcb.200202016. PMC 2173297. PMID 11980916.
^ "Entrez Gene: COG4 component of oligomeric golgi complex 4".
^ ^a ^b ^c ^d Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. 279 (23). United States: 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

External links

GeneReviews/NCBI/NIH/UW entry on Congenital Disorders of Glycosylation Overview
Human COG4 genome location and COG4 gene details page in the UCSC Genome Browser.

Template:PBB Controls

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000103051 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031753 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11980916-5] Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function". J Cell Biol. 157 (3): 405–15. doi:10.1083/jcb.200202016. PMC 2173297. PMID 11980916.

[entrez-6] "Entrez Gene: COG4 component of oligomeric golgi complex 4".

[pmid15047703-7] Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. 279 (23). United States: 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

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Interactions

References

Further reading

External links