Carbonic anhydrase 7

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CA7
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CA7, CAVII, carbonic anhydrase 7
External IDs MGI: 103100 HomoloGene: 55875 GeneCards: CA7
Gene location (Human)
Chromosome 16 (human)
Chr. Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for CA7
Genomic location for CA7
Band No data available Start 66,844,379 bp[1]
End 66,854,153 bp[1]
RNA expression pattern
PBB GE CA7 207504 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001014435
NM_005182

NM_001301164
NM_001301165
NM_053070

RefSeq (protein)

NP_001014435
NP_005173

NP_001288093
NP_001288094
NP_444300

Location (UCSC) Chr 16: 66.84 – 66.85 Mb Chr 16: 104.53 – 104.55 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Carbonic anhydrase 7 (CA7) is an enzyme that in humans is encoded by the CA7 gene.[5][6]

Function[edit]

Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168748 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031883 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Montgomery JC, Venta PJ, Eddy RL, Fukushima YS, Shows TB, Tashian RE (Dec 1991). "Characterization of the human gene for a newly discovered carbonic anhydrase, CA VII, and its localization to chromosome 16". Genomics. 11 (4): 835–48. PMID 1783392. doi:10.1016/0888-7543(91)90006-Z. 
  6. ^ a b "Entrez Gene: CA7 carbonic anhydrase VII". 

Further reading[edit]