Dominic Kwiatkowski
Dominic Kwiatkowski | |
|---|---|
 Dominic Kwiatkowski in 2013 | |
| Born | Dominic P. Kwiatkowski |
| Scientific career | |
| Fields | Genomics Malaria[1][2] |
| Institutions | Wellcome Sanger Institute University of Cambridge University of Oxford Guy's Hospital Leyland Motors[3] |
| Website | sanger |
Dominic Kwiatkowski FRS FMedSci FRCP[5][6] is head of the parasites and microbes programme at the Wellcome Sanger Institute[3] in Cambridge and a Professor of Genomics at the University of Oxford.[5] Kwiatkowski applies genomics and computational analysis to problems in infectious disease, with the aim of finding ways to reduce the burden of disease in the developing world.[5][4][7]
After training as a paediatrician at Guy's Hospital in London, Kwiatkowski spent several years in West Africa, where malaria causes high levels of infant mortality, and this has been a major focus of his research over the past thirty years.[5] He has made significant contributions to the understanding of malaria pathogenesis and genetic mechanisms of resistance to the disease.[5] He has also pioneered genome-wide association studies (GWAS) in Africa and has led large international collaborations to characterise the genomic diversity of parasite and mosquito populations around the world.[5] This work is yielding deep insights into the evolutionary biology of drug resistance and pesticide resistance with practical implications for disease control.[5]
In 2005 Kwiatkowski founded a data-sharing network, MalariaGEN, which has fostered productive research collaborations in more than forty malaria endemic countries, and has become a model for equitable sharing of genetic data and research capacity building in resource-poor settings.[5][1]
References
- ^ a b Hill, Adrian V. S.; Allsopp, Catherine E. M.; Kwiatkowski, Dominic; Anstey, Nicholas M.; Twumasi, Patrick; Rowe, Pamela A.; Bennett, Stephen; Brewster, David; McMichael, Andrew J.; Greenwood, Brian M. (1991). "Common West African HLA antigens are associated with protection from severe malaria". Nature. 352 (6336): 595–600. doi:10.1038/352595a0. ISSN 0028-0836. PMID 1865923.
- ^ Kwiatkowski, Dominic P. (2005). "How malaria has affected the human genome and what human genetics can teach us about malaria". American Journal of Human Genetics. 77 (2): 171–92. doi:10.1086/432519. PMC 1224522. PMID 16001361.
- ^ a b "Kwiatkowski, Dominic". sanger.ac.uk.
{{cite web}}: Cite has empty unknown parameter:|dead-url=(help) - ^ a b c "Professor Dominic Kwiatkowski - Nuffield Department of Medicine". www.ndm.ox.ac.uk.
- ^ a b c d e f g h Anon (2018). "Professor Dominic Kwiatkowski FMedSci FRS". royalsociety.org. London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
- ^ "Professor Dominic Kwiatkowski - The Academy of Medical Sciences". acmedsci.ac.uk.
- ^ Dominic Kwiatkowski publications from Europe PubMed Central
This article incorporates text available under the CC BY 4.0 license.
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