Duodenal cytochrome B
Appearance
cytochrome b reductase 1 | |||||||
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Identifiers | |||||||
Symbol | CYBRD1 | ||||||
Alt. symbols | DCYTB | ||||||
NCBI gene | 79901 | ||||||
HGNC | 20797 | ||||||
OMIM | 605745 | ||||||
RefSeq | NM_024843 | ||||||
UniProt | Q53TN4 | ||||||
Other data | |||||||
Locus | Chr. 2 q31 | ||||||
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Duodenal cytochrome B (Dcytb) has been identified as the reductase enzyme which catalyzes the reduction of Fe3+ to Fe2+ in the process of iron absorption in the duodenum of mammals.[1] According to research carried out, it appears that Dcytb upregulation is controlled by a number of independent stimulators or inhibitors of iron absorption. Furthermore, Dcytb has also been shown to exist in other tissues besides the apical region of the duodenum; and as such, it is believed to play a major role in iron metabolism in tissues.
References
- ^ Latunde-Dada GO, Van der Westhuizen J, Vulpe CD, et al. (2002). "Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolism". Blood Cells Mol. Dis. 29 (3): 356–60. doi:10.1006/bcmd.2002.0574. PMID 12547225.
External links
- duodenal+cytochrome+b,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)