Formylmethionine deformylase

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formylmethionine deformylase
Identifiers
EC number 3.5.1.31
CAS number 9032-86-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a formylmethionine deformylase (EC 3.5.1.31) is an enzyme that catalyzes the chemical reaction

N-formyl-L-methionine + H2O formate + L-methionine

Thus, the two substrates of this enzyme are N-formyl-L-methionine and H2O, whereas its two products are formate and L-methionine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-methionine amidohydrolase. This enzyme participates in methionine metabolism and glyoxylate and dicarboxylate metabolism.

Structural studies[edit]

As of late 2007, 14 structures have been solved for this class of enzymes, with PDB accession codes 1BS4, 1BS5, 1BS6, 1BS7, 1BS8, 1BSZ, 1DEF, 1DFF, 1G27, 1G2A, 1ICJ, 1JYM, 1RL4, and 2DEF.

References[edit]