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He became the host of American Public Media's Future Tense on May 3, 2010 Podcast/Broadcast. On Monday, September 20, 2010, Future Tense changed its name to Marketplace Tech Report as it became part of the Marketplace portfolio of programs. In September 2012, Moe left Marketplace Tech Report to devote his full-time attention to hosting the radio variety show Wits. Wits is a stage and radio show performed in the Fitzgerald Theater It began in 2010 and a podcast was created in 2012. The show consists of interviews, comedic sketches, musical performances, and a game show between the two guests, who have included George Takei, Maria Bamford, David Cross, and Neil Gaiman, among numerous others.
Previously, Moe was the host of American Public Media radio program Weekend America where he replaced show founder Bill Radke and Radke's co-host Desiree Cooper. Moe developed and wrote the weekly segment "A Little Bit of Weather Everywhere", presenting unique events happening around the country, and the weather for the day at these events. Prior to joining Weekend America full-time as a senior writer in 2007, Moe worked for NPR affiliate station KUOW-FM in Seattle,Washington where he hosted and produced The Works, a weekly program dedicated to business and technology.
He is the author of Dear Luke, We Need To Talk, Darth and Other Pop Culture Correspondences, published in June 2014. The book is a compilation of fictitious letters, notes, and messages based around familiar songs, movies, TV shows, and sporting events. He is also the author of Conservatize Me: How I Tried to Become a Righty with the Help of Richard Nixon, Sean Hannity, Toby Keith, and Beef Jerky, published in October 2006. The book chronicles Moe's attempt to become a conservative. The book contains several encounters with political experts, historians, and enthusiasts of all affiliations.
He has also appeared in the McSweeney's anthologies Created in Darkness by Troubled Americans, The McSweeney's Joke Book of Book Jokes, and Mountain Man Dance Moves.
He is also the author of Pop Song Correspondences, a feature on the McSweeney's web site, which is now a recurring segment on the Wits radio show.
He lives in St. Paul, Minnesota.
He previously worked at Amazon.com in an editorial capacity and at a staffing agency providing legal placement services.
In June 2015, Moe along with rapper Open Mike Eagle, launched "Conversation Parade", a podcast in which the two discuss the Cartoon Network animated series Adventure Time. The podcast has featured guests like Jeremy Shada (the voice of Finn the Human), John DiMaggio (the voice of Jake the Dog), Hynden Walch (the voice of Princess Bubblegum), and Adam Muto (the series' co-executive producer and showrunner), Kent Osborne (Adventure Time's head writer), Niki Yang (the voice of BMO and Lady Rainicorn), Olivia Olson (the voice of Marceline), Jesse Moynihan (former storyboard artist), Jessica DiCicco (the voice of Flame Princess), Elizabeth Ito (one of the show's supervising directors), and alternative country musician Neko Case.
- "Minnesota Public Radio News Names Jon Gordon Its First Social Media/Mobile Editor". MPR. 2010. Retrieved 2010-03-17.
- Moe, John , Tech Report Blog, September 17, 2010, accessed November 26, 2010
- "Moe leaving 'Marketplace Tech' to focus on 'Wits'". Pioneer Press. 2013. Retrieved 2013-01-04.
- Eagle, Mike; Moe, John (2015). "Conversation Parade: An Adventure Time Podcast". Infinite Guest Podcast Network. Retrieved June 27, 2015.
- Audio interview with Moe on public radio program The Sound of Young America
- Announcement of hosting change for Weekend America
- Pop Song Correspondences[dead link]