Nucleoporin 54

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NUP54
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases NUP54
External IDs MGI: 1920460 HomoloGene: 41169 GeneCards: 53371
RNA expression pattern
PBB GE NUP54 218256 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278603
NM_017426

NM_183392

RefSeq (protein)

NP_001265532.1
NP_059122.2

NP_899248.1

Location (UCSC) Chr 4: 76.11 – 76.15 Mb Chr 5: 92.42 – 92.44 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Nucleoporin 54 (Nup54) is a protein that in humans is encoded by the NUP54 gene.[1][2]

Function[edit]

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset.[2]

References[edit]

Further reading[edit]