Smith was working as a casting associate on The Office when she was offered the role of Phyllis, a character created specifically for her; a soft-spoken saleswoman who tends to disagree with the pompous office manager Michael Scott. She received Screen Actors Guild Awards in 2006 and 2007 for her performance in The Office, in the category "Outstanding Performance by an Ensemble in a Comedy Series". In June 2008, Smith appeared with the cast of The Office on Celebrity Family Feud. In 2011, she played a supporting role in the film Bad Teacher. In 2015, she voiced the character of Sadness in the Pixar film Inside Out.