Ribosome-nascent chain complex
Ribosome-nascent chain complex (RNC) refers to the collection of molecules that constitute a ribosome attached to the polypeptide (protein) that it is synthesising. The synthesis of the nascent polypeptide may be stalled by one of several methods. RNCs are produced and purified in laboratories to study the dynamics, biochemistry, folding and interactions of both the ribosome and proteins undergoing synthesis.
- Cabrita, Lisa D.; Dobson, Christopher M.; Christodoulou, John (2010). "Protein folding on the ribosome". Current Opinion in Structural Biology. 20: 33–45. doi:10.1016/j.sbi.2010.01.005.
- Schaffitzel, Christiane; Ban, Nenad (2007). "Generation of ribosome nascent chain complexes for structural and functional studies". Journal of Structural Biology. 158: 463–471. doi:10.1016/j.jsb.2007.01.005.
|This protein-related article is a stub. You can help Wikipedia by expanding it.|