Talk:Mir-194 microRNA precursor family

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miR-194 information from text mining[edit]

miR-194 Targets[edit]

Gene	EntrezID	Sentences
CDH2	EntrezID:1000	25096247 microrna-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting cdh2 and igf1r. See 4 More Sentences
IGF1R	EntrezID:3480	25096247 microrna-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting cdh2 and igf1r. See 3 More Sentences
ITSN1	EntrezID:16443	24197061 microrna-194 (mir-194) regulates romk channel activity by targeting intersectin 1. See 1 More Sentence
ITSN1	EntrezID:6453	24197061 expression of mir-194 mimic also decreased the translation of exogenous itsn1 in the cells transfected with the itsn1 containing 3'utr but not with 3'utr-free itsn1 See 2 More Sentences
NR2F2	EntrezID:386585	25412310 microrna-194 reciprocally stimulates osteogenesis and inhibits adipogenesis via regulating coup-tfii expression. See 2 More Sentences
NR2F2	EntrezID:7026	25800782 we showed evidence that hnf4gamma (upregulated in intestinal metaplasia) is targeted by mir-30 and that mir-194 targets a known co-regulator of hnf4 activity, nr2f2 (downregulated in intestinal metaplasia). See 1 More Sentence
BMI1	EntrezID:648	21851624 microrna-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene bmi-1. See 2 More Sentences
RBX1	EntrezID:9978	25412959 mir-194 targets rbx1 gene to modulate proliferation and migration of gastric cancer cells. See 2 More Sentences
CDKN1A	EntrezID:1026	22102710 mir-20a/b and mir-194 target cdkn1a and socs2 in follicular lymphoma, potentially contributing to tumor cell proliferation and survival. See 1 More Sentence
E2F1	EntrezID:1869	23213373 on the other hand, spherical cell shape-induced mir-194 and mir-320c would directly downregulate slc7a5 and e2f1 gene expression, respectively, which are both related to malignancy. See 1 More Sentence
FOXM1	EntrezID:2305	24748184 microrna-194 inhibits the epithelial-mesenchymal transition in gastric cancer cells by targeting foxm1. See 1 More Sentence
FZD6	EntrezID:14368	21887698 mir-194 also targets human fzd6 and expression of mir-194 and fzd6 are inversely correlated in a mouse model of hepatocellular carcinoma (dgcr8(flox/flox) p53(flox/flox) x alb-cre). See 1 More Sentence
MECP2	EntrezID:29386	17347136 further, irradiation significantly altered expression of mir-194, a mirna putatively targeting both dna methyltransferase-3a and mecp2. See 1 More Sentence
RAC1	EntrezID:363875	19892940 we conclude that both mirna-150 and mirna-194 inhibit hsc activation and ecm production, at least in part, via inhibition of c-myb and rac 1 expression. See 1 More Sentence
RUNX2	EntrezID:12393	25797619 taken together, our data suggest that mir-194 regulates osteoblast differentiation through modulating stat1-mediated runx2 nuclear translocation. See 1 More Sentence
SLC7A5	EntrezID:8140	23213373 on the other hand, spherical cell shape-induced mir-194 and mir-320c would directly downregulate slc7a5 and e2f1 gene expression, respectively, which are both related to malignancy. See 1 More Sentence
SOCS2	EntrezID:8835	22102710 mir-20a/b and mir-194 target cdkn1a and socs2 in follicular lymphoma, potentially contributing to tumor cell proliferation and survival. See 1 More Sentence
SOX5	EntrezID:6660	22396742 mir-194 regulates chondrogenic differentiation of human adipose-derived stem cells by targeting sox5. See 1 More Sentence
STAT1	EntrezID:20846	25797619 microrna-194 promotes osteoblast differentiation via downregulating stat1. See 1 More Sentence
TLN2	EntrezID:83660	22829924 increased mir-194 expression markedly reduced levels of the cytoskeletal protein talin2 and specifically inhibited luciferase reporter activity of a talin2 wild-type 3'-untranslated region, but not that of a mutant reporter, indicating that talin2 is a direct downstream target of mir-194. See 1 More Sentence
VIM	EntrezID:7431	21851624 ectopic expression of mir-194 in ec cells induced a mesenchymal to epithelial transition (met) by restoring e-cadherin, reducing vimentin expression, and inhibiting cell invasion in vitro. See 1 More Sentence
CD81 receptor	EntrezID:NA	25218426 mir-194 is a hepatocyte gate keeper hindering hcv entry through targeting cd81 receptor. See 8 More Sentences

miR-194 and Disease[edit]

Disease	Type	Sentences
DOID:3571: liver cancer	MARKER	20979124 mir-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. See 1 More Sentence
DOID:5758: malignant mesenchymoma	INVOLVED IN DISEASE	21851624 ectopic expression of mir-194 in ec cells induced a mesenchymal to epithelial transition ( met ) by restoring e-cadherin , reducing vimentin expression , and inhibiting cell invasion in_vitro. See 1 More Sentence

Carighi (talk) 13:36, 5 January 2016 (UTC)[reply]