Selenium responsive proteins

Selenium responsive proteins within human biology, are the class of proteins sensitive to selenium, in healthy human beings, in cancer patients, in in-vivo models or in-vitro cell culture models.

The original gi accession (version) numbers have been updated to NCBI accession number and protein names updated accordingly.^{[clarification needed]}

Accession Number	Common abbreviation	Protein name	Responsive in	Selenium compound	technique used	source
Q08091	CNN1	Calponin-1	TRAMP (prostate cancer mouse model)	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_035656	TAGLN	Transgelin	TRAMP (prostate cancer mouse model)	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_033822	APOA1	Apolipoprotein A-I	TRAMP (prostate cancer mouse model)	MSeC, MseA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_038499	ANXA4	Annexin A4	TRAMP (prostate cancer mouse model)	MseA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi21071030	A1BG	Alpha 1B-glycoprotein	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi4557871	TF	Transferrin	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi4502501	C4b	Complement component 4B proprotein	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
NP_059086	SEMG1	semenogelin I	TRAMP DLP UP	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
CAA47699	BGPG	Biliary glycoprotein	TRAMP DLP UP	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_780375	BASP1	brain acid soluble protein 1	TRAMP DLP UP	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_031789		Cysteine-rich protein 1	TRAMP DLP UP	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_059067	HPX	Hemopexin	TRAMP DLP UP	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi7305531		Seminal vesicle secretion 6	TRAMP DLP UP	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_780375	DMBTL_MOUSE	putative DMBT1-like protein precursor	TRAMP DLP UP	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6755212		Proteasome (prosome, macropain) 28 subunit, α	TRAMP DLP UP	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_035309	PSAP	Prosaposin	TRAMP DLP UP	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi123794006		FUSE-binding protein 2	TRAMP DLP UP	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi84875537		Nucleolin	TRAMP DLP UP	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi40254525		Tropomyosin 3, gamma	TRAMP DLP UP	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_032775	NUCB1	Nucleobindin 1	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi94717635		Progesterone receptor membrane component	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi21704156		Caldesmon 1	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi31980648		ATP synthase, H+ transporting mitochondrial F1 complex β	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi10946574		Creatine kinase, brain	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi94367355		Similar to 60S ribosomal protein L5	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi31981520		Pancreatic ribonuclease	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6754084		Glutathione S-transferase, mu 1	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6680121		Glutathione S-transferase, μ 2	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi31981302		Annexin A6	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6678740		Lumican	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi94403723		Similar to Heat shock 70-kDa protein 1B (HSP70.1)	TRAMP DLP DOWN	MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi89574165		Succinate dehydrogenase complex subunit A	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi70778915		Moesin	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6679567		Polymerase I and transcript release factor	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi31791059		Activated leukocyte cell adhesion molecule	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi76779293		Keratin 8	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6671549		Peroxiredoxin 6	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6680836		Calreticulin	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
NP_808579	TGM4	protein-glutamine gamma-glutamyltransferase 4	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi8567372		Probasin	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi2506545		78-kDa glucose-regulated protein precursor (GRP 78)	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi7643979		170-kDa glucose regulated protein GRP170	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi31542563		DnaJ (Hsp40) homolog, subfamily C, member 3	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi71774133		Peptidylprolyl isomerase B (PPI)	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi130232		Protein disulfide isomerase b family, ERp57 subfamily	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi129729		Protein disulfide isomerase ERp59	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi86198316		Protein disulfide isomerase associated 4	TRAMP DLP DOWN	MSeA	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi58037267		Protein disulfide isomerase-associated 6	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6753010		Anterior gradient 2	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi42794267		Experimental autoimmune prostatitis antigen 2	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi31543942		Vinculin	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi94387119		PREDICTED: similar to heat shock protein 8	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6752952		Actin, γ2, smooth muscle, enteric	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi94381948		PREDICTED: similar to Fc fragment of IgG binding protein	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi6754482		Keratin complex 1, acidic, gene 18	TRAMP DLP DOWN	MSeA, MSeC	iTRAQ LC-MS/MS	Zhang 2010 ^[1]
gi5031777		isocitrate dehydrogenase	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
NP_005134	HP	Haptoglobin isoform 1 preproprotein	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi42716297	CLU	Clusterin isoform 1	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi17318569		Keratin 1	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi4507725		Transthyretin	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi21361198	AAT	Alpha-1 antitrypsin	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi4557287		Angiotensin precursor	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]
gi4502027		Albumin precursor	Healthy Human blood serum	Selenium enriched yeast	2D DIGE LC-MS/MS	Sinha 2010 ^[2]

References

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab ^ac ^ad ^ae ^af ^ag ^ah ^ai ^aj ^ak ^al ^am ^an ^ao ^ap ^aq ^ar ^as ^at ^au ^av ^aw ^ax ^ay ^az Zhang, J.; Wang, L.; Anderson, L. B.; Witthuhn, B.; Xu, Y.; Lu, J. (2010). "Proteomic Profiling of Potential Molecular Targets of Methyl-Selenium Compounds in the Transgenic Adenocarcinoma of Mouse Prostate Model". Cancer Prevention Research. 3 (8): 994–1006. doi:10.1158/1940-6207.CAPR-09-0261. PMID 20647336.
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k Sinha, R.; Sinha, I.; Facompre, N.; Russell, S.; Somiari, R.; Richie Jr, J.; El-Bayoumy, K. (2010). "Selenium responsive proteins in sera of selenium-enriched yeast supplemented healthy African American and Caucasian men". Cancer Epidemiology, Biomarkers & Prevention. 19 (9): 2332–2340. doi:10.1158/1055-9965.EPI-10-0253. PMC 3326597. PMID 20643827.

[Zhang_2010-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab ^ac ^ad ^ae ^af ^ag ^ah ^ai ^aj ^ak ^al ^am ^an ^ao ^ap ^aq ^ar ^as ^at ^au ^av ^aw ^ax ^ay ^az Zhang, J.; Wang, L.; Anderson, L. B.; Witthuhn, B.; Xu, Y.; Lu, J. (2010). "Proteomic Profiling of Potential Molecular Targets of Methyl-Selenium Compounds in the Transgenic Adenocarcinoma of Mouse Prostate Model". Cancer Prevention Research. 3 (8): 994–1006. doi:10.1158/1940-6207.CAPR-09-0261. PMID 20647336.

[Sinha_2010-2] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k Sinha, R.; Sinha, I.; Facompre, N.; Russell, S.; Somiari, R.; Richie Jr, J.; El-Bayoumy, K. (2010). "Selenium responsive proteins in sera of selenium-enriched yeast supplemented healthy African American and Caucasian men". Cancer Epidemiology, Biomarkers & Prevention. 19 (9): 2332–2340. doi:10.1158/1055-9965.EPI-10-0253. PMC 3326597. PMID 20643827.

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