VectorBase

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VectorBase[1][2] is one of the five Bioinformatics Resource Centers (BRC) funded by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), which is an agency of the United States Department of Health and Human Services. VectorBase is focused on invertebrate vectors of human pathogens working with the sequencing centers and the research community to curate vector genomes (mainly genome annotation).

Genomes covered in the VectorBase database[edit]

Tools available through the VectorBase site[edit]

  • Genome browser
  • Community annotation system
  • Microarray and gene expression repository
  • Controlled vocabularies for anatomy,[5] insecticide resistance and vector-borne diseases (malaria and dengue fever)
  • BLAST searches for all covered genomes

See also[edit]

References[edit]

  1. ^ Lawson, D; Arensburger, P; Atkinson, P; Besansky, NJ; Bruggner, RV; Butler, R; Campbell, KS; Christophides, GK; et al. (2007). "VectorBase: a home for invertebrate vectors of human pathogens". Nucleic Acids Research. 35 (Database issue): D503–5. doi:10.1093/nar/gkl960. PMC 1751530Freely accessible. PMID 17145709. 
  2. ^ Lawson, D; Arensburger, P; Atkinson, P; Besansky, NJ; Bruggner, RV; Butler, R; Campbell, KS; Christophides, GK; et al. (2009). "VectorBase: a data resource for invertebrate vector genomics". Nucleic Acids Research. 37 (Database issue): D583–7. doi:10.1093/nar/gkn857. PMC 2686483Freely accessible. PMID 19028744. 
  3. ^ Nene, V; Wortman, JR; Lawson, D; Haas, B; Kodira, C; Tu, ZJ; Loftus, B; Xi, Z; et al. (2007). "Genome sequence of Aedes aegypti, a major arbovirus vector". Science. 316 (5832): 1718–23. Bibcode:2007Sci...316.1718N. doi:10.1126/science.1138878. PMC 2868357Freely accessible. PMID 17510324. 
  4. ^ Holt, RA; Subramanian, GM; Halpern, A; Sutton, GG; Charlab, R; Nusskern, DR; Wincker, P; Clark, AG; et al. (2002). "The genome sequence of the malaria mosquito Anopheles gambiae". Science. 298 (5591): 129–49. Bibcode:2002Sci...298..129H. doi:10.1126/science.1076181. PMID 12364791. 
  5. ^ Topalis, P; Tzavlaki, C; Vestaki, K; Dialynas, E; Sonenshine, DE; Butler, R; Bruggner, RV; Stinson, EO; et al. (2008). "Anatomical ontologies of mosquitoes and ticks, and their web browsers in VectorBase". Insect molecular biology. 17 (1): 87–9. doi:10.1111/j.1365-2583.2008.00781.x. PMID 18237287. 

External links[edit]

VectorBase genome browsers