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Glycoprotein O-fatty-acyltransferase

From Wikipedia, the free encyclopedia
glycoprotein O-fatty-acyltransferase
Identifiers
EC no.2.3.1.142
CAS no.122191-29-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a glycoprotein O-fatty-acyltransferase (EC 2.3.1.142) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + mucus glycoprotein CoA + O-palmitoylglycoprotein

Thus, the two substrates of this enzyme are palmitoyl-CoA and mucus glycoprotein, whereas its two products are CoA and O-palmitoylglycoprotein.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase. This enzyme is also called protein acyltransferase.

References

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  • Kasinathan C, Grzelinska E, Okazaki K, Slomiany BL, Slomiany A (1990). "Purification of protein fatty acyltransferase and determination of its distribution and topology". J. Biol. Chem. 265 (9): 5139–44. PMID 2318887.