Mast cell sarcoma: Difference between revisions

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| complications =
| complications =
| specialty = [[Oncology]]
| specialty = [[Oncology]]
| onset = Can occur at any age.<ref>Monnier J., Georgin-Lavialle S., Canioni D., Lhermitte L., Soussan M., Arock M., Bruneau J., Dubreuil P., Bodemer C., Chandesris M., Lortholary O., Hermine O., Damaj G. et al Mast cell sarcoma: new cases and literature review. Oncotarget. 2016; 7: 66299-66309. Retrieved from https://www.oncotarget.com/article/11812/text/</ref>
| onset = Can occur at any age.<ref>{{cite journal |last1=Monnier |first1=Jilliana |last2=Georgin-Lavialle |first2=Sophie |last3=Canioni |first3=Danielle |last4=Lhermitte |first4=Ludovic |last5=Soussan |first5=Michael |last6=Arock |first6=Michel |last7=Bruneau |first7=Julie |last8=Dubreuil |first8=Patrice |last9=Bodemer |first9=Christine |last10=Chandesris |first10=Marie-Olivia |last11=Lortholary |first11=Olivier |last12=Hermine |first12=Olivier |last13=Damaj |first13=Gandhi |title=Mast cell sarcoma: new cases and literature review |journal=Oncotarget |date=4 October 2016 |volume=7 |issue=40 |pages=66299–66309 |doi=10.18632/oncotarget.11812 |pmid=27602777 }}</ref>
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| duration =
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'''Mast cell sarcoma''' is an extremely aggressive<ref>{{cite journal |vauthors=Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P |title=Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma |journal=Am J Surg Pathol |volume=27 |issue=7 |pages=1013–9 |year=2003 |pmid=12826896 |doi=10.1097/00000478-200307000-00019|s2cid=46710032 }}</ref> form of [[sarcoma]] made up of neoplastic [[mast cell]]s. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. The largest analysis to date comprises 34 cases<ref>https://www.sciencedirect.com/science/article/pii/S089339522200076X?via%3Dihub </ref>. Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern.<ref>Nancy Gould, "[http://www.tmsforacure.org/research/consensus.shtml Diagnosis and Classification of Mastocytosis] {{webarchive|url=https://web.archive.org/web/20041027054546/http://www.tmsforacure.org/research/consensus.shtml |date=2004-10-27 }}", The Mastocytosis Society.</ref> Mast cell sarcoma should not be confused with
'''Mast cell sarcoma''' is an extremely aggressive<ref>{{cite journal |vauthors=Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P |title=Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma |journal=Am J Surg Pathol |volume=27 |issue=7 |pages=1013–9 |year=2003 |pmid=12826896 |doi=10.1097/00000478-200307000-00019|s2cid=46710032 }}</ref> form of [[sarcoma]] made up of neoplastic [[mast cell]]s. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. The largest analysis to date comprises 34 cases.<ref>{{cite journal |last1=Matsumoto |first1=Nana P. |last2=Yuan |first2=Ji |last3=Wang |first3=Jun |last4=Shen |first4=Qi |last5=Chen |first5=Xueyan |last6=Kim |first6=Young |last7=Zuppan |first7=Craig W. |last8=Chang |first8=Chung-Che |last9=Cui |first9=Wei |last10=Chen |first10=Dong |last11=Shi |first11=Min |last12=Gisriel |first12=Savanah D. |last13=Chen |first13=Mingyi |last14=Xu |first14=Mina L. |last15=Pan |first15=Zenggang |title=Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature |journal=Modern Pathology |date=July 2022 |volume=35 |issue=7 |pages=865–874 |doi=10.1038/s41379-022-01014-w }}</ref> Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern.<ref>Nancy Gould, "[http://www.tmsforacure.org/research/consensus.shtml Diagnosis and Classification of Mastocytosis] {{webarchive|url=https://web.archive.org/web/20041027054546/http://www.tmsforacure.org/research/consensus.shtml |date=2004-10-27 }}", The Mastocytosis Society.</ref> Mast cell sarcoma should not be confused with
extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as [[mast cell leukemia]]; one of the most aggressive human cancers.<ref>{{cite book |editor=Ansell SM |title=Rare Hematological Malignancies |publisher=Springer |series=Cancer Treatment & Research |year=2008 }}</ref>
extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as [[mast cell leukemia]]; one of the most aggressive human cancers.<ref>{{cite journal |doi=10.1007/978-0-387-73744-7 }}{{pn}}</ref>


==See also==
==See also==

Revision as of 00:14, 16 March 2024

Mast cell sarcoma
SpecialtyOncology
Usual onsetCan occur at any age.[1]
PrognosisThe median survival time is less than 18 months

Mast cell sarcoma is an extremely aggressive[2] form of sarcoma made up of neoplastic mast cells. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. The largest analysis to date comprises 34 cases.[3] Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern.[4] Mast cell sarcoma should not be confused with extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as mast cell leukemia; one of the most aggressive human cancers.[5]

See also

References

  1. ^ Monnier, Jilliana; Georgin-Lavialle, Sophie; Canioni, Danielle; Lhermitte, Ludovic; Soussan, Michael; Arock, Michel; Bruneau, Julie; Dubreuil, Patrice; Bodemer, Christine; Chandesris, Marie-Olivia; Lortholary, Olivier; Hermine, Olivier; Damaj, Gandhi (4 October 2016). "Mast cell sarcoma: new cases and literature review". Oncotarget. 7 (40): 66299–66309. doi:10.18632/oncotarget.11812. PMID 27602777.
  2. ^ Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P (2003). "Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma". Am J Surg Pathol. 27 (7): 1013–9. doi:10.1097/00000478-200307000-00019. PMID 12826896. S2CID 46710032.
  3. ^ Matsumoto, Nana P.; Yuan, Ji; Wang, Jun; Shen, Qi; Chen, Xueyan; Kim, Young; Zuppan, Craig W.; Chang, Chung-Che; Cui, Wei; Chen, Dong; Shi, Min; Gisriel, Savanah D.; Chen, Mingyi; Xu, Mina L.; Pan, Zenggang (July 2022). "Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature". Modern Pathology. 35 (7): 865–874. doi:10.1038/s41379-022-01014-w.
  4. ^ Nancy Gould, "Diagnosis and Classification of Mastocytosis Archived 2004-10-27 at the Wayback Machine", The Mastocytosis Society.
  5. ^ . doi:10.1007/978-0-387-73744-7. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)[page needed]

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